Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199837 | 0.87 | MMP2 (0.61) | ALDH1A1LMNAPKMGAAAR | |
| SCHEMBL8781070 | 0.87 | MMP2 (0.61) | ALDH1A1LMNAPKMGAAAR | |
| SCHEMBL13948497 | 0.79 | AR (0.60) | ALDH1A1LMNAPKMGAAAR | |
| SCHEMBL4199747 | 0.79 | AR (0.60) | ALDH1A1LMNAPKMGAAAR | |
| SCHEMBL15169739 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LMNAPKMGAAHPGD | |
| SCHEMBL15169281 | 0.78 | ALDH1A1 (0.60) | ALDH1A1LMNAPKMGAAHPGD | |
| SCHEMBL13948472 | 0.78 | ALDH1A1 (0.60) | ALDH1A1LMNAPKMGAAHPGD | |
| SCHEMBL20677146 | 0.77 | TDP1 (0.79) | ALDH1A1LMNAPKMGAAHPGD | |
| SCHEMBL21094081 | 0.77 | TDP1 (0.79) | ALDH1A1LMNAPKMGAAHPGD | |
| SCHEMBL50264 | 0.77 | TDP1 (0.79) | ALDH1A1LMNAPKMGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294800-A1 | APOL1 INHIBITORS AND METHODS OF USE | Maze Therapeutics, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |