Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887748 | 0.81 | MAPK1 (0.44) | MAPK1ALDH1A1TSHR | |
| Barium SCHEMBL10821630 | 0.78 | MAPK1 (0.42) | MAPK1ALDH1A1TSHR | |
| SCHEMBL18883358 | 0.75 | MAPK1 (0.35) | MAPK1ALDH1A1TSHR | |
| SCHEMBL12766261 | 0.75 | MAPK1 (0.35) | MAPK1ALDH1A1TSHR | |
| SCHEMBL7961211 | 0.73 | MAPK1 (0.33) | MAPK1ALDH1A1TSHR | |
| SCHEMBL17789952 | 0.71 | MAPK1 (0.32) | MAPK1ALDH1A1TSHR | |
| SCHEMBL6179854 | 0.71 | TSHR (0.32) | MAPK1ALDH1A1TSHR | |
| SCHEMBL6407706 | 0.69 | — | — | |
| SCHEMBL30468614 | 0.69 | — | — | |
| 1,4-Butanediol SCHEMBL5163849 | 0.67 | SMN1; SMN2 (0.35) | MAPK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858918-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858918-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | MAPK1 1118/4885ALDH1A1 3556/4885TSHR 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.