SCHEMBL887748

SCHEMBL887748

CC(C)CC(C)OC(C)CC(C)C

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.44
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
RNPEP Q9H4A4 1/20 0.35
SLC7A5 Q01650 1/20 0.35
ANPEP P15144 5/20 0.33
LAP3 P28838 2/20 0.33
ERAP1 Q9NZ08 2/20 0.33
ERAP2 Q6P179 1/20 0.32
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
NFKB1 P19838 1/20 0.30
THPO P40225 1/20 0.30
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Barium SCHEMBL10821630 0.96 MAPK1 (0.42) MAPK1ALDH1A1TSHRRNPEPSLC7A5
SCHEMBL12766261 0.86 MAPK1 (0.35) MAPK1ALDH1A1TSHRRNPEPSLC7A5
SCHEMBL18883358 0.86 MAPK1 (0.35) MAPK1ALDH1A1TSHRRNPEPSLC7A5
SCHEMBL7961211 0.83 MAPK1 (0.33) MAPK1ALDH1A1TSHRRNPEPSLC7A5
1,4-Butanediol SCHEMBL5163849 0.83 SMN1; SMN2 (0.35) MAPK1ALDH1A1TSHRRNPEPSLC7A5
SCHEMBL17789952 0.81 MAPK1 (0.32) MAPK1ALDH1A1TSHR
SCHEMBL6179854 0.81 TSHR (0.32) MAPK1ALDH1A1TSHRCYP3A4CYP2D6
SCHEMBL14321178 0.76 TSHR (0.40) TSHRRNPEPSLC7A5ANPEPLAP3
SCHEMBL32678948 0.75 TSHR (0.33) TSHR
SCHEMBL5718497 0.74 RNPEP (0.46) ALDH1A1RNPEPSLC7A5LAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 463 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10611865-B2 Organometallic compound in solid form, process for preparing the same and use thereof INDIAN OIL CORPORATION LIMITED (IN) 2020-04-07 US claimed
EP-2897966-B1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORP LTD (IN) 2020-04-01 EP claimed
EP-3018150-B1 PROCESS FOR THE PREPARATION OF SPHERICAL CATALYST PARTICLES INDIAN OIL CORP LTD (IN) 2020-03-11 EP claimed
EP-2966099-B1 PARTICLE SIZE DISTRIBUTION CONTROL THROUGH INTERNAL DONOR IN ZIEGLER-NATTA CATALYST INDIAN OIL CORP LTD (IN) 2020-03-11 EP claimed
US-20180355082-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2018-12-13 US claimed
US-10100136-B2 Organometallic compound in solid form, process for preparing the same and use thereof INDIAN OIL CORPORATION LIMITED (IN) 2018-10-16 US claimed
CN-106632451-A Norbornylene-alkyl-dialkoxysilane and preparation method thereof 临邑县鲁晶化工有限公司 2017-05-10 CN claimed
US-9644050-B2 Particle size distribution control through internal donor in Ziegler-Natta catalyst INDIAN OIL CORPORATION LIMITED (IN) 2017-05-09 US claimed
US-20170081440-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF INDIAN OIL CORPORATION LIMITED (IN) 2017-03-23 US claimed
US-9587041-B2 Organometallic compound in solid form, process for preparing the same and use thereof INDIAN OIL CORPORATION LIMITED (IN) 2017-03-07 US claimed
CN-1902208-A Grignard processes with improved yields of diphenylchlorosilanes as products DOW CORNING (US) 2007-01-24 CN claimed
EP-1701965-A1 GRIGNARD PROCESSES WITH INCREASED CONTENT OF DIPHENYLCHLOROSILANES Dow Corning Corporation (US) 2006-09-20 EP claimed
EP-1701964-A1 GRIGNARD PROCESSES WITH IMPROVED YIELDS OF DIPHENYLCHLOROSILANES AS PRODUCTS Dow Corning Corporation (US) 2006-09-20 EP claimed
WO-2005068475-A1 GRIGNARD PROCESSES WITH IMPROVED YIELDS OF DIPHENYLCHLOROSILANES AS PRODUCTS DOW CORNING CORPORATION (US) 2005-07-28 WO claimed
WO-2005068476-A1 GRIGNARD PROCESSES WITH INCREASED CONTENT OF DIPHENYLCHLOROSILANES DOW CORNING CORPORATION (US) 2005-07-28 WO claimed
US-6331501-B1 COORDINATION CATALYST COMPRIMISING ORGANOSILICON,-MAGNESIUM, -ALUMINUM AND -TITANIUM COMPOUNDS; TITANIUM TETRACHLORIDE, ACYL HALIDE, ESTER AND ETHER; POWDER PROPERTIES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-18 US claimed
EP-0162908-A4 PREPARATION OF ALKALINE EARTH METAL ORGANOMETALLIC COMPOUNDS. LITHIUM CORP (US) 1986-04-15 EP claimed
EP-0162908-A1 PREPARATION OF ALKALINE EARTH METAL ORGANOMETALLIC COMPOUNDS LITHIUM CORPORATION OF AMERICA (US) 1985-12-04 EP claimed
US-4555498-A Preparation of certain alkaline earth metal organometallic compounds LITHIUM CORPORATION OF AMERICA (US) 1985-11-26 US claimed
WO-1985002176-A1 PREPARATION OF ALKALINE EARTH METAL ORGANOMETALLIC COMPOUNDS LITHIUM CORPORATION OF AMERICA (US) 1985-05-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180355082-A1 ORGANOMETALLIC COMPOUND IN SOLID FORM, PROCESS FOR PREPARING THE SAME AND USE THEREOF MLX, BRIX1, CYP4X1 MAPK1 2962/4885ALDH1A1 1126/4885TSHR 2774/4885
US-10611865-B2 Organometallic compound in solid form, process for preparing the same and use thereof MLX, BRIX1, CYP4X1 MAPK1 2962/4885ALDH1A1 1126/4885TSHR 2774/4885
US-10100136-B2 Organometallic compound in solid form, process for preparing the same and use thereof MLX, BRIX1, CYP4X1 MAPK1 2962/4885ALDH1A1 1126/4885TSHR 2774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.