Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATP4A | P20648 | 1/20 | 0.46 |
| ▸ | ATP4B | P51164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MGMT | P16455 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747871 | 0.80 | L3MBTL1 (0.74) | L3MBTL1HTTSTAT3SMN1; SMN2ATP4A | |
| SCHEMBL28485531 | 0.80 | L3MBTL1 (0.64) | L3MBTL1HTTSTAT3SMN1; SMN2HPGD | |
| SCHEMBL27301730 | 0.77 | L3MBTL1 (0.56) | L3MBTL1HTTSTAT3SMN1; SMN2ATP4A | |
| SCHEMBL31093748 | 0.76 | L3MBTL1 (0.48) | L3MBTL1HTTSTAT3SMN1; SMN2ATP4A | |
| SCHEMBL18080647 | 0.76 | L3MBTL1 (0.48) | L3MBTL1HTTSTAT3SMN1; SMN2ATP4A | |
| SCHEMBL11225394 | 0.76 | L3MBTL1 (0.58) | L3MBTL1HTTSTAT3SMN1; SMN2ATP4A | |
| SCHEMBL26971407 | 0.76 | L3MBTL1 (0.54) | L3MBTL1HTTSTAT3SMN1; SMN2ATP4A | |
| SCHEMBL11225846 | 0.76 | L3MBTL1 (0.58) | L3MBTL1HTTSTAT3SMN1; SMN2ATP4A | |
| SCHEMBL18080646 | 0.75 | L3MBTL1 (0.53) | L3MBTL1HTTSTAT3SMN1; SMN2ATP4A | |
| SCHEMBL19128629 | 0.75 | L3MBTL1 (0.57) | L3MBTL1HTTSTAT3SMN1; SMN2ATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858916-B2 | GLP-1 receptor agonists and uses thereof | PFIZER INC. (US) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858916-B2 | GLP-1 receptor agonists and uses thereof | GLP1R, GIPR, GCGR | L3MBTL1 1713/4885HTT 2727/4885STAT3 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.