SCHEMBL269751

SCHEMBL269751

CCOC=CC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1878756 1.00
SCHEMBL8593221 0.81 CASP1 (0.44)
SCHEMBL9084392 0.81 CASP1 (0.44)
SCHEMBL20223367 0.80 CASP1 (0.41)
SCHEMBL8534873 0.80
SCHEMBL8534874 0.80
SCHEMBL278041 0.79
SCHEMBL20589645 0.79
SCHEMBL932916 0.79
SCHEMBL10335471 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115403522-A Biphenyl quinoline skeleton compound with C2 axis chirality, chiral isomer thereof, preparation method and application thereof 中国科学院成都有机化学有限公司 2022-11-29 CN disclosed
WO-2020025499-A1 NEW COMPONENTS FOR ELECTROLYTE COMPOSITIONS SOLVAY SA (BE) 2020-02-06 WO disclosed
EP-3605698-A1 NEW COMPONENTS FOR ELECTROLYTE COMPOSITIONS SOLVAY SA (BE) 2020-02-05 EP disclosed
US-20190031617-A1 PROCESS FOR THE MANUFACTURE OF CARBOXAMIDES SOLVAY SA (BE) 2019-01-31 US disclosed
EP-3416949-A1 PROCESS FOR THE MANUFACTURE OF CARBOXAMIDES SOLVAY SA (BE) 2018-12-26 EP disclosed
WO-2017140593-A1 PROCESS FOR THE MANUFACTURE OF CARBOXAMIDES SOLVAY SA (BE) 2017-08-24 WO disclosed
US-8133907-B2 Type II diabetes, obesity, hyperglycemia and a lipid disorder selected from dyslipidemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, low HDL and high LDL; additionally comprising metformin ELI LILLY AND COMPANY (US) 2012-03-13 US disclosed
EP-2158205-B1 3,3-SPIROINDOLINONE DERIVATIVES AS ANTICANCER AGENTS HOFFMANN LA ROCHE (CH) 2011-12-07 EP disclosed
US-7939674-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-10 US disclosed
US-7700642-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
US-20080287421-A1 3,3-SPIROINDOLINONE DERIVATIVES LIU JIN-JUN 2008-11-20 US disclosed
US-20080221337-A1 Process for Producing an Aromatic Unsaturated Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-11 US disclosed
US-20080214616-A1 Pyridine Derivatives as Dipeptedyl Peptidase Inhibitors ELI LILLY AND COMPANY 2008-09-04 US disclosed
EP-1826202-A1 Process for the preparation of furan compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-08-29 EP disclosed
US-20070197806-A1 Process for the preparation of furan compounds DAICEL CHEMICAL INDUSTRIES, LTD. 2007-08-23 US disclosed
EP-1666440-A1 METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND Sumitomo Chemical Company, Limited (JP) 2006-06-07 EP disclosed
EP-0764625-B1 Process for improving the storability of liquid hydroxy- and alkoxyalkylketones BASF AG (DE) 1999-04-07 EP disclosed
US-5874631-A ADDING FROM 0.0001 TO 1% BY WEIGHT OF A TERTIARY AMINE, OR GROUP 1A AND 2A HYDROXIDES AND CARBONATES OR MIXTURES THEREOF BASF AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5767295-A REACTING ALDEHYDE WITH SILANOL-SUBSTITUTED BUTADIENE IN THE PRESENCE OF A LEWIS ACID KANEKA CORPORATION (JP) 1998-06-16 US disclosed
EP-0764625-A1 Process for improving the storability of liquid hydroxy- and alkoxyalkylketones BASF AKTIENGESELLSCHAFT (DE) 1997-03-26 EP disclosed