Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9084392 | 1.00 | CASP1 (0.44) | CASP1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL20223367 | 0.87 | CASP1 (0.41) | CASP1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL4192225 | 0.87 | CASP1 (0.41) | CASP1HCAR2ALDH1A1 | |
| SCHEMBL4192228 | 0.87 | CASP1 (0.41) | CASP1HCAR2ALDH1A1 | |
| SCHEMBL18037713 | 0.85 | CASP1 (0.40) | CASP1HCAR2 | |
| SCHEMBL16371556 | 0.85 | CASP1 (0.40) | CASP1HCAR2 | |
| SCHEMBL983246 | 0.84 | NPSR1 (0.42) | CASP1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL983248 | 0.84 | NPSR1 (0.42) | CASP1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL2651775 | 0.84 | CASP1 (0.39) | CASP1HCAR2ALDH1A1MGAMGAA | |
| SCHEMBL2651778 | 0.84 | CASP1 (0.39) | CASP1HCAR2ALDH1A1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587072-B1 | Process for the preparation of alpha, beta-unsaturated beta-oxycarboxylic acid chlorides | BASF AG (DE) | 1998-01-07 | — | — | EP | disclosed |
| US-5543568-A | Preparation of α,β-unsaturated β-oxycarboxylic acid chlorides | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-06 | — | — | US | disclosed |
| EP-0587072-A1 | Process for the preparation of alpha, beta-unsaturated beta-oxycarboxylic acid chlorides | BASF Aktiengesellschaft (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-4774359-A | Polyenamines from aromatic diacetylenic diketones and diamines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1988-09-27 | — | — | US | disclosed |
| US-4663483-A | Polyenamines from aromatic diacetylenic diketones and diamines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1987-05-05 | — | — | US | disclosed |