⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096273 | 0.82 | KMT2A (0.39) | — | |
| SCHEMBL4721673 | 0.80 | LMNA (0.44) | — | |
| SCHEMBL1534886 | 0.77 | ALDH1A1 (0.42) | — | |
| Biphenyl SCHEMBL30897406 | 0.71 | ALDH1A1 (0.90) | — | |
| Biphenyl SCHEMBL7846472 | 0.71 | ALDH1A1 (0.90) | — | |
| Biphenyl SCHEMBL7080242 | 0.71 | ALDH1A1 (0.90) | — | |
| Biphenyl SCHEMBL9388941 | 0.68 | ALDH1A1 (0.82) | — | |
| Biphenyl SCHEMBL1950579 | 0.67 | ALDH1A1 (0.64) | — | |
| SCHEMBL23277163 | 0.67 | ALDH1A1 (0.44) | — | |
| Biphenyl SCHEMBL2548048 | 0.67 | ALDH1A1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3693426-A1 | ANTIFOULING PAINT COMPOSITION AND COATED ARTICLE HAVING ANTIFOULING COATING FORMED USING SAID COMPOSITION ON SURFACE | Nitto Kasei Co., Ltd. (JP) | 2020-08-12 | — | — | EP | claimed |
| US-20090118290-A1 | Indoleacetic acid and indenacetic acid derivatives as therapeutic agents with reduced gastrointestinal toxicity | VANDERBILT UNIVERSITY | 2009-05-07 | — | — | US | claimed |
| EP-1744747-A2 | INDOLEACETIC ACID AND INDENACETIC ACID DERIVATIVES AS THERAPEUTIC AGENTS WITH REDUCED GASTROINTESTINAL TOXICITY | Vanderbilt University (US) | 2007-01-24 | — | — | EP | claimed |
| WO-2005112921-A2 | INDOLEACETIC ACID AND INDENACETIC ACID DERIVATIVES AS THERAPEUTIC AGENTS WITH REDUCED GASTROINTESTINAL TOXICITY | VANDERBILT UNIVERSITY (US) | 2005-12-01 | — | — | WO | claimed |
| US-20050250839-A1 | Indoleacetic acid and indenacetic acid derivatives as therapeutic agents with reduced gastrointestinal toxicity | VANDERBILT UNIVERSITY | 2005-11-10 | — | — | US | claimed |
| EP-3693426-B1 | ANTIFOULING PAINT COMPOSITION AND COATED ARTICLE HAVING ANTIFOULING COATING FORMED USING SAID COMPOSITION ON SURFACE | NITTO KASEI CO LTD (JP) | 2021-12-29 | — | — | EP | disclosed |
| EP-3693426-A1 | ANTIFOULING PAINT COMPOSITION AND COATED ARTICLE HAVING ANTIFOULING COATING FORMED USING SAID COMPOSITION ON SURFACE | Nitto Kasei Co., Ltd. (JP) | 2020-08-12 | — | — | EP | disclosed |
| US-8168656-B2 | Indoleacetic acid and indenacetic acid derivatives as therapeutic agents with reduced gastrointestinal toxicity | VANDERBILT UNIVERSITY (US) | 2012-05-01 | — | — | US | disclosed |
| US-20090118290-A1 | Indoleacetic acid and indenacetic acid derivatives as therapeutic agents with reduced gastrointestinal toxicity | VANDERBILT UNIVERSITY | 2009-05-07 | — | — | US | disclosed |
| US-7491744-B2 | Indoleacetic acid and indenacetic acid derivatives as therapeutic agents with reduced gastrointestinal toxicity | VANDERBILT UNIVERSITY (US) | 2009-02-17 | — | — | US | disclosed |
| EP-1744747-A2 | INDOLEACETIC ACID AND INDENACETIC ACID DERIVATIVES AS THERAPEUTIC AGENTS WITH REDUCED GASTROINTESTINAL TOXICITY | Vanderbilt University (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005112921-A2 | INDOLEACETIC ACID AND INDENACETIC ACID DERIVATIVES AS THERAPEUTIC AGENTS WITH REDUCED GASTROINTESTINAL TOXICITY | VANDERBILT UNIVERSITY (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050250839-A1 | Indoleacetic acid and indenacetic acid derivatives as therapeutic agents with reduced gastrointestinal toxicity | VANDERBILT UNIVERSITY | 2005-11-10 | — | — | US | disclosed |