Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 15/20 | 0.51 |
| ▸ | JAK2 | O60674 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.41 |
| ▸ | AURKA | O14965 | 5/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478361 | 0.81 | JAK2 (0.58) | PDPK1JAK2KDM4ECYP3A4GAA | |
| SCHEMBL30882695 | 0.80 | PDPK1 (0.56) | PDPK1JAK2KDM4ECYP3A4GAA | |
| SCHEMBL5391597 | 0.80 | PDPK1 (0.56) | PDPK1JAK2KDM4ECYP3A4GAA | |
| SCHEMBL11753776 | 0.80 | PDPK1 (0.49) | PDPK1JAK2KDM4ECYP3A4GAA | |
| SCHEMBL11963111 | 0.79 | PDPK1 (0.47) | PDPK1JAK2KDM4ECYP3A4GAA | |
| SCHEMBL4559295 | 0.79 | SGK1 (0.49) | PDPK1JAK2SGK1 | |
| SCHEMBL91579 | 0.79 | PDPK1 (0.55) | PDPK1JAK2KDM4ECYP3A4GAA | |
| SCHEMBL2144862 | 0.79 | PDPK1 (0.59) | PDPK1JAK2KDM4ECYP3A4GAA | |
| Hydrochloric Acid SCHEMBL7425346 | 0.79 | PDPK1 (0.55) | PDPK1JAK2KDM4ECYP3A4GAA | |
| SCHEMBL5430903 | 0.76 | PRKAG1 (0.53) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3871673-B1 | NOVEL INDAZOLE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2024-01-03 | — | — | EP | disclosed |