SCHEMBL26977331

SCHEMBL26977331

O=C(O)/C=C/C(=O)OC1CCC1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.49
HCAR2 Q8TDS4 7/20 0.43
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
EGLN3 Q9H6Z9 1/20 0.39
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
POLB P06746 1/20 0.38
HRH1 P35367 2/20 0.35
EPHX1 P07099 2/20 0.35
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4165033 1.00 ATM (0.49) ATMHCAR2TSHRTP53EGLN1
SCHEMBL505930 1.00 ATM (0.49) ATMHCAR2TSHRTP53EGLN1
SCHEMBL528296 0.96 ATM (0.49) ATMHCAR2TSHRTP53EGLN1
SCHEMBL528295 0.96 ATM (0.49) ATMHCAR2TSHRTP53EGLN1
SCHEMBL609184 0.96 ATM (0.49) ATMHCAR2TSHRTP53EGLN1
SCHEMBL4158798 0.94 ATM (0.47) ATMHCAR2TSHRTP53EGLN1
Cyclohexyl Fumarate SCHEMBL528630 0.94 ATM (0.47) ATMHCAR2TSHRTP53EGLN1
Fumaric Acid SCHEMBL7564862 0.94 ATM (0.47) ATMHCAR2TSHRTP53EGLN1
SCHEMBL1087406 0.94 ATM (0.47) ATMHCAR2TSHRTP53EGLN1
Cyclohexyl Fumarate SCHEMBL528629 0.94 ATM (0.47) ATMHCAR2TSHRTP53EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
EP-4299283-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-01-03 EP disclosed
CN-117157337-A Fumaric acid diester resin, film and polarizing plate 东曹株式会社 2023-12-01 CN disclosed
WO-2022210589-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE 東ソー株式会社 2022-10-06 WO disclosed