SCHEMBL505930

SCHEMBL505930

O=C(O)/C=C\C(=O)OC1CCC1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.49
HCAR2 Q8TDS4 7/20 0.43
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39
EGLN3 Q9H6Z9 1/20 0.39
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
POLB P06746 1/20 0.38
HRH1 P35367 2/20 0.35
EPHX1 P07099 2/20 0.35
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4165033 1.00 ATM (0.49) ATMHCAR2TSHRTP53EGLN1
SCHEMBL26977331 1.00 ATM (0.49) ATMHCAR2TSHRTP53EGLN1
SCHEMBL528296 0.96 ATM (0.49) ATMHCAR2TSHRTP53EGLN1
SCHEMBL528295 0.96 ATM (0.49) ATMHCAR2TSHRTP53EGLN1
SCHEMBL609184 0.96 ATM (0.49) ATMHCAR2TSHRTP53EGLN1
SCHEMBL4158798 0.94 ATM (0.47) ATMHCAR2TSHRTP53EGLN1
Cyclohexyl Fumarate SCHEMBL528630 0.94 ATM (0.47) ATMHCAR2TSHRTP53EGLN1
Fumaric Acid SCHEMBL7564862 0.94 ATM (0.47) ATMHCAR2TSHRTP53EGLN1
SCHEMBL1087406 0.94 ATM (0.47) ATMHCAR2TSHRTP53EGLN1
Cyclohexyl Fumarate SCHEMBL528629 0.94 ATM (0.47) ATMHCAR2TSHRTP53EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070105984-A1 Composition comprising cellulose and polyvinyl chloride polymer E. I. DU PONT DE NEMOURS AND COMPANY 2007-05-10 US claimed
EP-2736714-B1 MULTILAYER FILMS FOR RECLOSABLE PACKAGING PERFORMANCE MAT NA INC (US) 2021-03-24 EP disclosed
EP-2933097-B1 CROSSLINKABLE MATERIALS FOR SAFETY LAMINATES PERFORMANCE MAT NA INC (US) 2021-01-20 EP disclosed
US-10569517-B2 Selectively permeable ethylene copolymer compositions PERFORMANCE MATERIALS NA, INC. (US) 2020-02-25 US disclosed
US-10435550-B2 Variable vapor barrier for humidity control PERFORMANCE MATERIALS NA, INC. (US) 2019-10-08 US disclosed
EP-2358526-B1 LAMINATED ARTICLES COMPRISING A SHEET OF A BLEND OF ETHYLENE COPOLYMERS DU PONT (US) 2018-08-29 EP disclosed
US-20180178496-A1 SELECTIVELY PERMEABLE ETHYLENE COPOLYMER COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2018-06-28 US disclosed
US-9777145-B2 Anti-fogging films based on ethylene copolymer compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-10-03 US disclosed
US-9777181-B2 Antistatic ethylene copolymer compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-10-03 US disclosed
US-20160303837-A1 SELECTIVELY PERMEABLE ETHYLENE COPOLYMER COMPOSITIONS PERFORMANCE MATERIALS NA, INC. 2016-10-20 US disclosed
US-20050203253-A1 Ethylene copolymer-modified polyamide product DOW GLOBAL TECHNOLOGIES LLC 2005-09-15 US disclosed
WO-2005080496-A1 COMPOSITE COMPOSITIONS COMPRISING CELLULOSE AND POLYMERIC COMPONENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-09-01 WO disclosed
US-20050187315-A1 Composite compositions comprising cellulose and polymeric components E. I. DU PONT DE NEMOURS AND COMPANY 2005-08-25 US disclosed
US-20050112372-A1 Ethylene copolymer modified oriented polyester films, tapes, fibers and nonwoven textiles CELANESE POLYMERS HOLDING, INC. 2005-05-26 US disclosed
WO-2005040257-A1 ETHYLENE COPOLYMER MODIFIED ORIENTED POLYESTER FILMS, TAPES, FIBERS AND NONWOVEN TEXTILES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-05-06 WO disclosed
EP-0140530-B1 LATENTLY-CURABLE ORGANOSILICONE RELEASE COATING COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-08 EP disclosed
US-4533575-A ETHYLENICALLY UNSATURATED POLYSILOXANE AND POLYHYDROSILOXANE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-08-06 US disclosed
EP-0140530-A1 Latently-curable organosilicone release coating composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-08 EP disclosed
US-4504645-A GELATION INHIBITION USING A MONOESTER OR -AMIDE OF AN UNSATURATED DICARBOXYLIC ACID; SHELF LIFE; HEAT CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-12 US disclosed
US-4174358-A Tough thermoplastic nylon compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-11-13 US disclosed