Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanide SCHEMBL25406844 | 0.81 | LMNA (0.44) | LMNAMAOBMAPTKDM4EHTT | |
| SCHEMBL15652066 | 0.81 | LMNA (0.53) | LMNAMAOBMAPTDAODYRK1A | |
| SCHEMBL10138689 | 0.74 | LMNA (0.53) | LMNAMAOBMAPTDAODYRK1A | |
| SCHEMBL25318060 | 0.74 | LMNA (0.56) | LMNAMAOBMAPTKDM4EDAO | |
| SCHEMBL3263393 | 0.72 | DAO (0.66) | LMNAMAOBMAPTDAOTP53 | |
| SCHEMBL3066593 | 0.70 | LMNA (0.57) | LMNAMAOBMAPTDAOPGR | |
| SCHEMBL25041248 | 0.70 | KDM4E (0.43) | MAPTKDM4EPKMGAAALDH1A1 | |
| SCHEMBL1639030 | 0.70 | LMNA (0.56) | LMNAMAOBMAPTKDM4EDAO | |
| SCHEMBL31053821 | 0.70 | LMNA (0.56) | LMNAMAOBMAPTDAOTP53 | |
| SCHEMBL31192592 | 0.70 | DAO (0.64) | LMNAMAOBMAPTKDM4EDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021904-B1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-01-03 | — | — | EP | disclosed |