Guaiazulen

Guaiazulen

SCHEMBL26982

Cc1ccc(C(C)C)cc2c(C)ccc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
PTGS1 P23219 2/20 0.58
TRPA1 O75762 1/20 0.58
CACNA1C Q13936 1/20 0.58
HTT P42858 2/20 0.40
ALDH1A1 P00352 2/20 0.40
GAA P10253 1/20 0.40
ALOX12 P18054 1/20 0.40
HIF1A Q16665 1/20 0.40
ACHE P22303 5/20 0.39
BCHE P06276 4/20 0.39
PTGS2 P35354 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
RNASEH1 O60930 1/20 0.38
HPGD P15428 1/20 0.37
GFER P55789 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PDK2 Q15119 1/20 0.37
TYR P14679 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guaiazulen SCHEMBL29259925 1.00 LMNA (1.00) LMNAPTGS1TRPA1CACNA1CHTT
Guaiazulen SCHEMBL29639620 1.00 LMNA (1.00) LMNAPTGS1TRPA1CACNA1CHTT
Guaiazulen SCHEMBL27806695 0.98 LMNA (0.95) LMNAPTGS1TRPA1CACNA1CHTT
Guaiazulen SCHEMBL7916824 0.98 LMNA (0.95) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL31051327 0.95 LMNA (0.90) LMNAPTGS1TRPA1CACNA1CHTT
SCHEMBL10416092 0.93 LMNA (0.86) LMNAPTGS1TRPA1CACNA1CHTT
Guaiazulen SCHEMBL28588570 0.88 LMNA (0.77) LMNAPTGS1TRPA1CACNA1CACHE
SCHEMBL20676163 0.87 LMNA (0.77) LMNAPTGS1TRPA1CACNA1CHTT
Guaiazulen SCHEMBL28572432 0.86 LMNA (0.74) LMNAPTGS1TRPA1CACNA1CACHE
SCHEMBL12515665 0.81 LMNA (0.68) LMNAPTGS1TRPA1CACNA1CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7492 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146168-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2026-05-28 US claimed
EP-4655386-A1 GENETIC MODIFICATION OF MICROBES FOR PRODUCTION OF CARBON-CONTAINING NON-NITROGEN COMPOUNDS Fertis India Pvt Ltd (IN) 2025-12-03 EP claimed
US-12398702-B2 Method and system using small molecule absorbers to create a photothermal actuator THE REGENTS OF THE UNIVERSITY OF CALIFORNI (US) 2025-08-26 US claimed
US-20250248400-A1 NANOPARTICULATE FORMULATION FOR PREVENTING OR TREATING CALLOSE FORMATION IN PLANTS PURDUE RESEARCH FOUNDATION (US) 2025-08-07 US claimed
US-20250064700-A1 COMPOSITIONS, PRODUCTS, SYSTEM, AND METHOD FOR PERMING HAIR Curl Cult LLC (US) 2025-02-27 US claimed
WO-2024248087-A1 METHOD FOR PRODUCING GUAIAZULENE 日本新薬株式会社 2024-12-05 WO claimed
US-12121602-B2 Anhydrous sunscreen composition, process of manufacturing the anhydrous sunscreen composition and use of the anhydrous sunscreen composition L'OREAL (FR) 2024-10-22 US claimed
US-20240317779-A1 METAL COMPLEXES HAVING 4-H,6-H OR 8-H DIHYDROAZULENYL LIGANDS AND USE THEREOF UMICORE AG & CO. KG (DE) 2024-09-26 US claimed
US-12091570-B2 Polymer composite photonic crystal coatings COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2024-09-17 US claimed
US-20240245703-A1 TOPICAL APPLICATION OF AGENTS TO REDUCE SUN SENSITIVITY AND IMPROVE TOPICAL PHOTODYNAMIC THERAPY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-07-25 US claimed
EP-0227836-B1 SUSTAINED RELEASING PATCH TEIJIN LIMITED (JP) 1991-12-27 EP claimed
EP-0211559-B1 PHOTORECEPTOR FOR ELECTROGRAPHY KONICA CORPORATION (JP) 1991-12-11 EP claimed
US-5028506-A Layer Containing A Charge-Generating Substance On An Electroconductive Substrate KONICA CORPORATION (JP) 1991-07-02 US claimed
US-4879274-A IMPROVED ABSORPTION KAO CORPORATION (JP) 1989-11-07 US claimed
US-4801458-A POROUS HOLLOW FIBERS FILLED WITH MEDICINE TEIJIN LIMITED (JP) 1989-01-31 US claimed
US-4751075-A Anhydrous cosmetic compositions for thermal skin treatments REDKEN LABORATORIES, INC. (US) 1988-06-14 US claimed
US-4737360-A POLLEN EXTRACT AND VEGETABLE OILS CERNITIN AMERICA, INC. (US) 1988-04-12 US claimed
EP-0227836-A1 SUSTAINED RELEASING PATCH TEIJIN LIMITED (JP) 1987-07-08 EP claimed
US-4656043-A SUITABLE FOR TREATING PERMANENTLY WAVED HAIR RICHARDSON-VICKS INC. (US) 1987-04-07 US claimed
EP-0211559-A1 Photoreceptor for electrography KONICA CORPORATION (JP) 1987-02-25 EP claimed