Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guaiazulen SCHEMBL26982 | 1.00 | LMNA (1.00) | LMNAPTGS1TRPA1CACNA1CHTT | |
| Guaiazulen SCHEMBL29259925 | 1.00 | LMNA (1.00) | LMNAPTGS1TRPA1CACNA1CHTT | |
| Guaiazulen SCHEMBL27806695 | 0.98 | LMNA (0.95) | LMNAPTGS1TRPA1CACNA1CHTT | |
| Guaiazulen SCHEMBL7916824 | 0.98 | LMNA (0.95) | LMNAPTGS1TRPA1CACNA1CHTT | |
| SCHEMBL31051327 | 0.95 | LMNA (0.90) | LMNAPTGS1TRPA1CACNA1CHTT | |
| SCHEMBL10416092 | 0.93 | LMNA (0.86) | LMNAPTGS1TRPA1CACNA1CHTT | |
| Guaiazulen SCHEMBL28588570 | 0.88 | LMNA (0.77) | LMNAPTGS1TRPA1CACNA1CACHE | |
| SCHEMBL20676163 | 0.87 | LMNA (0.77) | LMNAPTGS1TRPA1CACNA1CHTT | |
| Guaiazulen SCHEMBL28572432 | 0.86 | LMNA (0.74) | LMNAPTGS1TRPA1CACNA1CACHE | |
| SCHEMBL12515665 | 0.81 | LMNA (0.68) | LMNAPTGS1TRPA1CACNA1CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398702-B2 | Method and system using small molecule absorbers to create a photothermal actuator | THE REGENTS OF THE UNIVERSITY OF CALIFORNI (US) | 2025-08-26 | — | — | US | claimed |
| CN-117534592-A | Method for synthesizing 1, 4-dimethyl-7-isopropyl azulene-3-sodium sulfonate | 许荧 | 2024-02-09 | — | — | CN | claimed |
| CN-117074572-A | Method for detecting related substances of 1, 4-dimethyl-7-isopropyl azulene-3-sodium sulfonate and related preparations thereof | 成都阿奇生物医药科技有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-116917295-A | Metal complexes with 4-H, 6-H or 8-H-dihydroazulene ligands and uses thereof | 优米科尔股份公司及两合公司 | 2023-10-20 | — | — | CN | claimed |
| US-20230332581-A1 | METHOD AND SYSTEM USING SMALL MOLECULE ABSORBERS TO CREATE A PHOTOTHERMAL ACTUATOR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-10-19 | — | — | US | claimed |
| EP-4047003-A1 | METAL COMPLEXES WITH 4-H-, 6-H- OR 8-H-DIHYDROAZULENYL LIGANDS AND THEIR USE | UMICORE AG & Co. KG (DE) | 2022-08-24 | — | — | EP | claimed |
| US-12414977-B2 | Method of administering seaberry and saw palmetto extracts to inhibit 5α-reductase activity | ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) | 2025-09-16 | — | — | US | disclosed |
| US-20250268972-A1 | 5a-REDUCTASE INHIBITOR | ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) | 2025-08-28 | — | — | US | disclosed |
| US-12398702-B2 | Method and system using small molecule absorbers to create a photothermal actuator | THE REGENTS OF THE UNIVERSITY OF CALIFORNI (US) | 2025-08-26 | — | — | US | disclosed |
| US-12398702-B2 | Method and system using small molecule absorbers to create a photothermal actuator | THE REGENTS OF THE UNIVERSITY OF CALIFORNI (US) | 2025-08-26 | — | — | US | disclosed |
| CN-114929340-B | Methods and agents for glaucoma | 奥夫博医疗创新有限公司 | 2025-06-10 | — | — | CN | disclosed |
| US-12221495-B2 | Cyclic peptide and a medicament, external preparation and cosmetic comprising said cyclic peptide | IGISU CO., LTD. (JP) | 2025-02-11 | — | — | US | disclosed |
| CN-118806612-B | Oil-in-oil microcapsule loaded with guaazulene and preparation method and application thereof | 杭州岛屿星晴生物技术有限公司 | 2024-12-20 | — | — | CN | disclosed |
| WO-2022175112-A1 | NOBLE METAL COMPLEXES WITH DIHYDROAZULENYL LIGANDS AND USE THEREOF | UMICORE AG & CO. KG (DE) | 2022-08-25 | — | — | WO | disclosed |
| EP-4047003-A1 | METAL COMPLEXES WITH 4-H-, 6-H- OR 8-H-DIHYDROAZULENYL LIGANDS AND THEIR USE | UMICORE AG & Co. KG (DE) | 2022-08-24 | — | — | EP | disclosed |
| CN-114929340-A | Methods and agents for glaucoma | 奥夫博医疗创新有限公司 | 2022-08-19 | — | — | CN | disclosed |
| EP-4031244-A1 | PROCESSES AND AGENTS FOR GLAUCOMA | Aufbau Medical Innovations Limited (IE) | 2022-07-27 | — | — | EP | disclosed |
| US-20220211800-A1 | PROCESSES AND AGENTS FOR GLAUCOMA | CORNELL UNIVERSITY (US) | 2022-07-07 | — | — | US | disclosed |
| EP-4014987-A2 | CYCLIC PEPTIDE, AND MEDICINE, EXTERNAL PREPARATION AND COSMETIC EACH CONTAINING SAID CYCLIC PEPTIDE | Igisu Co., Ltd. (JP) | 2022-06-22 | — | — | EP | disclosed |
| CN-114441571-A | Method for determining molecular structure based on three-dimensional electron diffraction | 苏州青云瑞晶生物科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220211800-A1 | PROCESSES AND AGENTS FOR GLAUCOMA | RHOA, PDE6C, EXOSC10 | LMNA 2151/4885PTGS1 110/4885TRPA1 1288/4885 |
| US-12221495-B2 | Cyclic peptide and a medicament, external preparation and cosmetic comprising said cyclic peptide | TSLP, NPR1, VIP | LMNA 4657/4885PTGS1 1115/4885TRPA1 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.