SCHEMBL2698323

SCHEMBL2698323

CC(=O)C(Cl)C(=O)N(C)C

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196589 1.00 ALDH1A1 (0.38) ALDH1A1TSHRLMNAGAAMAPT
SCHEMBL53472 0.75
SCHEMBL288972 0.73
SCHEMBL11474106 0.72 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL29010312 0.72
Silver SCHEMBL30466753 0.72
SCHEMBL5317805 0.71
SCHEMBL4276493 0.69
Chloroform SCHEMBL11172190 0.69 ALDH1A1 (0.47) ALDH1A1TSHRLMNAMAPT
SCHEMBL6117942 0.69 ALDH1A1 (0.33) ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4214002-A FUNGICIDES, BACTERICIDES GIVAUDAN CORPORATION (US) 1980-07-22 US claimed
US-20250109245-A1 PREPARATION OF UNSATURATED POLYESTERS EASTMAN CHEMICAL COMPANY (US) 2025-04-03 US disclosed
EP-4473036-A1 PREPARATION OF UNSATURATED POLYESTERS Eastman Chemical Company (US) 2024-12-11 EP disclosed
WO-2023147330-A1 PREPARATION OF UNSATURATED POLYESTERS EASTMAN CHEMICAL COMPANY (US) 2023-08-03 WO disclosed
US-9376594-B2 Polishing composition FUJIMI INCORPORATED (JP) 2016-06-28 US disclosed
US-20150069016-A1 POLISHING COMPOSITION FUJIMI INCORPORATED (JP) 2015-03-12 US disclosed
US-8198299-B2 Cycloalkylidene and heterocycloalkylidene inhibitor compounds GILEAD SCIENCES, INC. (US) 2012-06-12 US disclosed
WO-2012073259-A1 NOVEL PROCESS FOR THE PREPARATION OF FEBUXOSTAT INDOCO REMEDIES LIMITED (IN) 2012-06-07 WO disclosed
US-20120045412-A1 CYCLOALKYLIDENE AND HETEROCYCLOALKYLIDENE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2012-02-23 US disclosed
US-8088771-B2 Cycloalkylidene and heterocycloalkylidene inhibitor compounds GILEAD SCIENCES, INC. (US) 2012-01-03 US disclosed
US-4353923-A MUSCLE RELAXANTS, ANTIINFLAMMATORY, ANALGESIC KYOWA HAKKO KOGYO CO., LTD. (JP) 1982-10-12 US disclosed
EP-0005849-B1 PROCESS FOR PREPARING ALPHA-CHLORO-N-MONOALKYL-ACETOACETAMIDES Wacker-Chemie GmbH (DE) 1981-10-21 EP disclosed
US-4260765-A APHIDICIDES UNIROYAL, INC. (US) 1981-04-07 US disclosed
US-4247712-A ANTIMICROBIAL GIVAUDAN CORPORATION (US) 1981-01-27 US disclosed
US-4235818-A Process for producing alpha-monochloroacetoacetic acid monomethylamide CIBA-GEIGY CORPORATION (US) 1980-11-25 US disclosed
US-4214002-A FUNGICIDES, BACTERICIDES GIVAUDAN CORPORATION (US) 1980-07-22 US disclosed
US-4207259-A WATER AS SOLVENT WACKER-CHEMIE GMBH (DE) 1980-06-10 US disclosed
EP-0005849-A1 Process for preparing alpha-chloro-N-monoalkyl-acetoacetamides Wacker-Chemie GmbH (DE) 1979-12-12 EP disclosed
US-4080457-A INSECTICIDES, PESTICIDES, MITICIDES UNIROYAL CHEMICAL COMPANY, INC. 1978-03-21 US disclosed
US-4046759-A INTERMEDIATES FOR CEPHALOSPORINS ISHIMARU TOSHIYASU 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120045412-A1 CYCLOALKYLIDENE AND HETEROCYCLOALKYLIDENE INHIBITOR COMPOUNDS HDAC1, HDAC11, HDAC2 ALDH1A1 957/4885TSHR 3874/4885LMNA 1594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.