SCHEMBL288972

SCHEMBL288972

CN(C)C(=O)C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL14691155 0.91 ALDH1A1 (0.38)
Methylene Chloride SCHEMBL1359188 0.91 ALDH1A1 (0.38)
SCHEMBL5317805 0.78
SCHEMBL11592801 0.78
SCHEMBL4679759 0.75
SCHEMBL26216799 0.75
Hydrochloric Acid SCHEMBL30950660 0.75
SCHEMBL2698323 0.73 ALDH1A1 (0.38)
SCHEMBL196589 0.73 ALDH1A1 (0.38)
SCHEMBL27974916 0.73 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 668 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109721577-A A kind of purification process of furans dicarboxylic acids 中国科学院宁波材料技术与工程研究所 2019-05-07 CN claimed
CN-105646454-B The 2- aryl amine pyridine derivatives of the fragment containing hydroxamic acid and preparation and application 浙江大学 2018-05-08 CN claimed
CN-102875379-A Industrialized synthetic method of ethyl difuoroacetate SHANGHAI PINWO CHEMICAL CO LTD 2013-01-16 CN claimed
WO-2024120750-A1 A PHARMACEUTICAL FORMULATION COMPRISING POLYMERIC MICRO-/NANOFIBERS INCORPORATING ECHINOCHROME A NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) 2024-06-13 WO disclosed
CN-113677349-B Structured molecular carriers for anti-inflammatory compounds and uses thereof 克洛德贝纳尔-里昂第一大学 2024-03-19 CN disclosed
CN-114057727-B Synthesis method of zolpidem intermediate 株洲千金药业股份有限公司 2024-02-27 CN disclosed
CN-117447348-A Synthesis method of difluoroacetamide compound 辽宁优创植物保护有限公司 2024-01-26 CN disclosed
CN-114057725-B Synthesis method of zolpidem tartrate 株洲千金药业股份有限公司 2024-01-16 CN disclosed
EP-4253421-A2 ANTI-HER2 BIPARATOPIC ANTIBODY-DRUG CONJUGATES AND METHODS OF USE Zymeworks BC Inc. (CA) 2023-10-04 EP disclosed
EP-4219526-A2 METHOD FOR PREPARING AMG 416 AMGEN, INC. (US) 2023-08-02 EP disclosed
US-11708384-B2 Systems and methods for mechanosynthesis CBN NANO TECHNOLOGIES INC. (CA) 2023-07-25 US disclosed
US-4140697-A ARTIFICIAL SWEETENER HOFFMANN-LA ROCHE INC. (US) 1979-02-20 US disclosed
US-4133805-A INHIBIT RELEASE OR PITUITARY GROWTH HORMONE, GLUCAGON, AND INSULIN AMERICAN HOME PRODUCTS CORPORATION (US) 1979-01-09 US disclosed
US-4102877-A REACTION OF AN OLIGOPEPTIDE WITH ISOPROPYLCARBODIIMIDE BOND TO POLYSTYRENE MERCK & CO., INC. (US) 1978-07-25 US disclosed
US-4089946-A Claudogenic-interceptive nonapeptides AMERICAN HOME PRODUCTS CORPORATION (US) 1978-05-16 US disclosed
US-4073795-A Synthesis of tryptophans HOFFMANN-LA ROCHE INC. (US) 1978-02-14 US disclosed
US-4054558-A DIEBETES MELLITUS, ACROMEGALY AMERICAN HOME PRODUCTS CORPORATION (US) 1977-10-18 US disclosed
US-4033756-A PROTECTIVE COATINGS GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-07-05 US disclosed
US-4000259-A DIABETES AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-28 US disclosed
US-3988304-A Cyclic dodecapeptide derivatives of somatostatin and intermediates thereof AMERICAN HOME PRODUCTS CORPORATION (US) 1976-10-26 US disclosed