Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 8/20 | 0.37 |
| ▸ | FLT1 | P17948 | 7/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.37 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 4/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984868 | 0.92 | NUDT1 (0.42) | NUDT1KDRFLT1FGFR1TRPM5 | |
| SCHEMBL30746708 | 0.84 | NUDT1 (0.42) | NUDT1KDRFLT1FGFR1TRPM5 | |
| SCHEMBL26985138 | 0.84 | NUDT1 (0.42) | NUDT1KDRFLT1FGFR1TRPM5 | |
| SCHEMBL26984929 | 0.83 | NUDT1 (0.41) | NUDT1KDRFLT1FGFR1TRPM5 | |
| SCHEMBL30746421 | 0.83 | NUDT1 (0.41) | NUDT1KDRFLT1FGFR1TRPM5 | |
| SCHEMBL30746407 | 0.82 | KDR (0.41) | NUDT1KDRFLT1FGFR1TRPM5 | |
| SCHEMBL26985004 | 0.82 | KDR (0.41) | NUDT1KDRFLT1FGFR1TRPM5 | |
| SCHEMBL30746604 | 0.81 | DHFR (0.34) | CSF1RDHFR | |
| SCHEMBL30746454 | 0.81 | KDM4E (0.35) | NUDT1KDRFLT1CSF1RDHFR | |
| SCHEMBL26985336 | 0.81 | DHFR (0.34) | CSF1RDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |