Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | KDM5A | P29375 | 5/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770177 | 0.98 | LMNA (0.52) | LMNAS1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL15080033 | 0.98 | LMNA (0.52) | LMNAS1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL11675407 | 0.98 | LMNA (0.52) | LMNAS1PR2S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL10882256 | 0.96 | LMNA (0.50) | LMNAS1PR2S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL1094941 | 0.96 | LMNA (0.50) | LMNAS1PR2S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL23754223 | 0.96 | LMNA (0.50) | LMNAS1PR2S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL28789529 | 0.96 | LMNA (0.50) | LMNAS1PR2S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL4642402 | 0.96 | LMNA (0.50) | LMNAS1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL10608034 | 0.94 | LMNA (0.52) | LMNAS1PR2S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL17969271 | 0.92 | LMNA (0.50) | LMNAS1PR2S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024009250-A1 | FUNCTIONALIZED SILICA PARTICLES, OBTENTION AND USES THEREOF | CENTITVC - CENTRO DE NANOTECNOLOGIA E MATERIAIS TÉCNICOS FUNCIONAIS E INTELIGENTES (PT) | 2024-01-11 | — | — | WO | claimed |