Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 known ✓ | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 known ✓ | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 known ✓ | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 known ✓ | Q9H228 | 1/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.35 |
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.35 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.35 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.45 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10882256 | 1.00 | LMNA (0.50) | LMNADNM1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL28789529 | 1.00 | LMNA (0.50) | LMNADNM1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL23754223 | 1.00 | LMNA (0.50) | LMNADNM1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL4642402 | 1.00 | LMNA (0.50) | LMNADNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL7770177 | 0.98 | LMNA (0.52) | LMNADNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL11675407 | 0.98 | LMNA (0.52) | LMNADNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL15080033 | 0.98 | LMNA (0.52) | LMNADNM1S1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL17969271 | 0.96 | LMNA (0.50) | LMNADNM1S1PR2S1PR1S1PR3 | |
| Iodide SCHEMBL26985709 | 0.96 | LMNA (0.50) | LMNADNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL10608034 | 0.94 | LMNA (0.52) | LMNADNM1S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470497-B2 | Two-component developer having a resin coated carrier for electrophotography and toner | PANASONIC CORPORATION (JP) | 2008-12-30 | — | — | US | claimed |
| US-20060051695-A1 | Carrier for electrophotography | PANASONIC CORPORATION (JP) | 2006-03-09 | — | — | US | claimed |
| US-20060014094-A1 | Two-component developer and method of forming image therewith | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-01-19 | — | — | US | claimed |
| EP-1553460-A1 | CARRIER FOR ELECTROPHOTOGRAPHY | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-07-13 | — | — | EP | claimed |
| US-6196156-B1 | Bedding articles possessing microbe-inhibiting properties | SEEFAR TECHNOLOGIES, INC. | 2001-03-06 | — | — | US | claimed |
| US-5164105-A | Polysiloxane/polysilsesquioxanes with quaternary ammonium groups dispersed in dielectric oil | BRIDGESTONE CORPORATION (JP) | 1992-11-17 | — | — | US | claimed |
| CN-114958316-B | Organic soil for oil-based drilling fluid and preparation method thereof | 中国石油天然气集团有限公司 | 2023-06-20 | — | — | CN | disclosed |
| EP-4103635-A1 | POLYURETHANE FOAM COMPOSITIONS WITH ANTIMICROBIAL PROPERTIES | Sanitized AG (CH) | 2022-12-21 | — | — | EP | disclosed |
| CN-114958316-A | Organic soil for oil-based drilling fluid and preparation method thereof | 中国石油天然气集团有限公司 | 2022-08-30 | — | — | CN | disclosed |
| WO-2021160757-A1 | POLYURETHANE FOAM COMPOSITIONS WITH ANTIMICROBIAL PROPERTIES | SANITIZED AG (CH) | 2021-08-19 | — | — | WO | disclosed |
| US-8153342-B2 | Developer, and image forming apparatus and image forming method using the developer | RICOH COMPANY, LTD. (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20110165510-A1 | TONER, PROCESS FOR PRODUCING TONER, AND TWO-COMPONENT DEVELOPING AGENT | PANASONIC CORPORATION (JP) | 2011-07-07 | — | — | US | disclosed |
| US-7939232-B2 | Base particles obtained by mixing in aqueous medium a resin particle dispersion, a colorant dispersion, a wax dispersion; ensures low-temperature melting for low-temperature fixability, high-temperature offset resistance, and high-temperature storage stability, and also has small uniform particle size | PANASONIC CORPORATION (JP) | 2011-05-10 | — | — | US | disclosed |
| US-20080206665-A1 | Toner, method for producing toner, two component developer, and image forming apparatus | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2008-08-28 | — | — | US | disclosed |
| US-20080069594-A1 | Developer, and image forming apparatus and image forming method using the developer | RICOH COMPANY, LTD. (JP) | 2008-03-20 | — | — | US | disclosed |
| US-20060057482-A1 | Toner, two-component developer, and image forming method | MATSUSHITA ELECTRIC INDUSTRIAL CO. (JP) | 2006-03-16 | — | — | US | disclosed |
| US-20060051695-A1 | Carrier for electrophotography | PANASONIC CORPORATION (JP) | 2006-03-09 | — | — | US | disclosed |
| US-20060014094-A1 | Two-component developer and method of forming image therewith | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-01-19 | — | — | US | disclosed |
| EP-1553460-A1 | CARRIER FOR ELECTROPHOTOGRAPHY | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-07-13 | — | — | EP | disclosed |
| US-5164105-A | Polysiloxane/polysilsesquioxanes with quaternary ammonium groups dispersed in dielectric oil | BRIDGESTONE CORPORATION (JP) | 1992-11-17 | — | — | US | disclosed |