Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26988756 | 0.83 | POLQ (0.35) | PROKR1IMPDH2POLQ | |
| SCHEMBL1344896 | 0.78 | NOS3 (0.52) | PROKR1CYP1A2CYP3A4ALOX15TSHR | |
| SCHEMBL19192034 | 0.76 | CYP1A2 (0.41) | PROKR1IMPDH2CYP1A2CYP3A4ALOX15 | |
| SCHEMBL803102 | 0.72 | CYP1A2 (0.40) | PROKR1IMPDH2CYP1A2CYP3A4ALOX15 | |
| SCHEMBL5700095 | 0.72 | EED (0.39) | PROKR1APPCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL3677277 | 0.71 | TRPV1 (0.41) | APPTSHR | |
| SCHEMBL26988715 | 0.69 | MAPT (0.42) | PROKR1MAPK1 | |
| SCHEMBL20987610 | 0.68 | CNR2 (0.33) | IMPDH2MAPK1EEDDYRK1AADORA2A | |
| SCHEMBL3216629 | 0.65 | NOS3 (0.53) | CYP1A2CYP3A4ALOX15TSHRMAPK1 | |
| SCHEMBL19135622 | 0.64 | CNR2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008909-A1 | INHIBITORS OF CORONAVIRUS | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-11 | — | — | WO | disclosed |