Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGFR | P43088 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872046 | 0.84 | LMNA (0.52) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL31588310 | 0.84 | LMNA (0.52) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL21990472 | 0.83 | TBXA2R (0.37) | MEN1KMT2AALDH1A1TBXA2RPTGER3 | |
| SCHEMBL6853616 | 0.82 | MEN1 (0.46) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL7453987 | 0.81 | LMNA (0.60) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL12869653 | 0.81 | ALDH1A1 (0.47) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL10727696 | 0.81 | ALDH1A1 (0.52) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL11464004 | 0.81 | MEN1 (0.44) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL38665606 | 0.81 | ERN1 (0.50) | ALDH1A1MAOAMAOBERN1 | |
| SCHEMBL9018908 | 0.81 | ALDH1A1 (0.46) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008909-A1 | INHIBITORS OF CORONAVIRUS | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-11 | — | — | WO | disclosed |
| CN-108084448-B | Cadmium polymerization complex containing 4, 5-dimethyl-1, 2-phenylenediamine derivative and preparation method and application thereof | 湘潭大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-108084448-A | One kind -1,2- of dimethyl containing 4,5- phenylenediamine derivatives close cadmium oligometric comples and preparation method and purposes | 湘潭大学 | 2018-05-29 | — | — | CN | disclosed |