Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.80 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.80 |
| ▸ | NQO2 | P16083 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393644 | 0.89 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL26989676 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL26989714 | 0.81 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL7894816 | 0.79 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL26989677 | 0.78 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL26989162 | 0.76 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL31543690 | 0.75 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL1311849 | 0.75 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL7894811 | 0.73 | MTNR1A (0.71) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9667084 | 0.73 | MTNR1A (0.65) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008341-A1 | SEROTONIN ANALOGUES FOR USE IN TREATING METALLOPTOSIS-ASSOCIATED DISORDERS | INSTITUT CURIE (FR) | 2024-01-11 | — | — | WO | disclosed |