Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.80 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.80 |
| ▸ | NQO2 | P16083 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311849 | 0.89 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL31543690 | 0.83 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL26989688 | 0.81 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL6765219 | 0.79 | NQO2 (0.76) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL9667084 | 0.78 | MTNR1A (0.65) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9326663 | 0.77 | MTNR1A (0.81) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL30630419 | 0.77 | MTNR1A (0.81) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL26989162 | 0.76 | MTNR1A (0.80) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL14175652 | 0.76 | MTNR1A (0.76) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL31530480 | 0.76 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008341-A1 | SEROTONIN ANALOGUES FOR USE IN TREATING METALLOPTOSIS-ASSOCIATED DISORDERS | INSTITUT CURIE (FR) | 2024-01-11 | — | — | WO | disclosed |