Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | DHPS | P49366 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840685 | 0.81 | WDR91 (0.51) | WDR91DRD2ADRA1ADRD3DHPS | |
| SCHEMBL24973 | 0.74 | SMYD3 (0.58) | — | |
| SCHEMBL26301 | 0.74 | SMYD3 (0.71) | — | |
| SCHEMBL9836689 | 0.72 | CRBN (0.49) | WDR91DRD2ADRA1ADRD3DHPS | |
| SCHEMBL13163153 | 0.71 | HPGD (0.64) | MEN1KMT2A | |
| SCHEMBL5362141 | 0.71 | CCNB2 (0.48) | WDR91DRD2DHPS | |
| SCHEMBL4407214 | 0.70 | CRBN (0.50) | WDR91DRD2MEN1KMT2AADRA1A | |
| SCHEMBL4410729 | 0.70 | DRD2 (0.50) | WDR91DRD2ADRA1ADRD3DHPS | |
| SCHEMBL18946096 | 0.70 | TSHR (0.53) | DRD2MEN1KMT2ADRD3 | |
| SCHEMBL31310315 | 0.70 | CREBBP (0.46) | WDR91DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025726-A1 | Novel Hybrid Compounds | UNIVERSITY OF GREENWICH (GB) | 2012-03-01 | — | — | WO | disclosed |