Androsterone

Androsterone

SCHEMBL269981

C[C@]12CC[C@@H](O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 5/20 1.00
GPBAR1 Q8TDU6 4/20 1.00
LMNA P02545 3/20 1.00
CYP3A4 P08684 3/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
SHBG P04278 2/20 1.00
SERPINA6 P08185 2/20 1.00
MAPK1 P28482 2/20 1.00
HSD17B3 P37058 1/20 1.00
PMP22 Q01453 1/20 1.00
AKR1B10 O60218 1/20 1.00
AKR1B1 P15121 1/20 1.00
CYP2D6 P10635 1/20 1.00
TSHR P16473 1/20 1.00
NFKB1 P19838 1/20 1.00
CYP2C19 P33261 1/20 1.00
ALDH1A1 P00352 1/20 0.67
TP53 P04637 1/20 0.67
MAPT P10636 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Androsterone SCHEMBL10273502 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL269982 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL13175783 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Epiandrosterone SCHEMBL295167 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL12811704 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL15426610 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL23031469 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL9940929 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL19750468 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL21114416 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5936 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260148848-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-05-28 US claimed
US-20260140124-A1 PCOS STRATIFICATION THE UNIVERSITY OF BIRMINGHAM (GB) 2026-05-21 US claimed
EP-4740024-A1 ENDOMETRIOSIS MARKERS AND METHODS OF DIAGNOSING ENDOMETRIOSIS The University Court Of The University of Edinburgh (GB) 2026-05-13 EP claimed
US-12569501-B2 Neurosteroids and enantiomers thereof for the prevention and treatment of neurodegenerative conditions WASHINGTON UNIVERSITY (US) 2026-03-10 US claimed
US-20250361548-A1 ENHANCED SMALL MOLECULE DETECTION AND QUANTITATIVE ANALYSIS AVETA LIFE INC (US) 2025-11-27 US claimed
EP-4605743-A1 PCOS STRATIFICATION The University of Birmingham (GB) 2025-08-27 EP claimed
US-20250213589-A1 METHODS AND COMPOSITIONS FOR TESTOSTERONE PRODUCTION Maximus Health, Inc. (US) 2025-07-03 US claimed
EP-4562182-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2025-06-04 EP claimed
WO-2025096781-A1 METHODS AND COMPOSITIONS FOR PROVIDING CUSTOMIZED SKIN REGIMENS VIBRANT HOLDINGS, LLC (US) 2025-05-08 WO claimed
CN-115963199-B Quantitative detection method and application of steroid hormone in human/animal body fluid 上海鹿明生物科技有限公司 2025-04-29 CN claimed
EP-0199768-A1 A METHOD FOR THE PREVENTION OF OCULAR HYPERTENSION, TREATMENT OF GLAUCOMA AND TREATMENT OF OCULAR HYPERTENSION KNEPPER, Paul A. (US) 1986-11-05 EP claimed
EP-0084537-B1 METHOD AND MEANS FOR REPELLING ANIMALS NORDTEND A/S (NO) 1986-10-15 EP claimed
US-4617299-A ADMINISTERING SELECTED ANABOLIC ANDROGENIC COMPOUNDS KNEPPER PAUL A (US) 1986-10-14 US claimed
WO-1986002554-A1 A METHOD FOR THE PREVENTION OF OCULAR HYPERTENSION, TREATMENT OF GLAUCOMA AND TREATMENT OF OCULAR HYPERTENSION KNEPPER PAUL A 1986-05-09 WO claimed
US-4534976-A STEROIDS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1985-08-13 US claimed
US-4451460-A WITH HUMAN STEROIDS NORDTEND A/S (NO) 1984-05-29 US claimed
EP-0084537-A1 METHOD AND MEANS FOR REPELLING ANIMALS. NORDTEND AS (NO) 1983-08-03 EP claimed
WO-1983000417-A1 METHOD AND MEANS FOR REPELLING ANIMALS HANSEN, HELGE 1983-02-17 WO claimed
US-4321208-A Preparation of directly iodinated steroid hormones and related compounds SAHADEVAN VELAYUDHAN 1982-03-23 US claimed
US-3962430-A Sterilization of solid non-electrolyte medicinal agents employing sodium chloride MERCK & CO., INC. (US) 1976-06-08 US claimed