Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 9/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | STK4 | Q13043 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26998207 | 0.94 | MAP3K14 (0.37) | MAP3K14PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL26999118 | 0.89 | PTPN11 (0.40) | MAP3K14FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL25424012 | 0.88 | MAP3K14 (0.38) | MAP3K14ROCK2ROCK1 | |
| SCHEMBL26998152 | 0.87 | MAP3K14 (0.36) | MAP3K14ROCK2ROCK1 | |
| SCHEMBL26998160 | 0.87 | MAP3K14 (0.36) | MAP3K14ROCK2ROCK1 | |
| SCHEMBL26998155 | 0.86 | ROCK2 (0.36) | MAP3K14PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL26998153 | 0.85 | ROCK2 (0.36) | MAP3K14ROCK2ROCK1 | |
| SCHEMBL26998214 | 0.84 | MAP3K14 (0.35) | MAP3K14ROCK2ROCK1 | |
| SCHEMBL25427115 | 0.84 | MAP3K14 (0.38) | MAP3K14ROCK2ROCK1PIM1PIM2 | |
| SCHEMBL26999119 | 0.83 | PIM1 (0.34) | MAP3K14ROCK2ROCK1PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | MAP3K14 2494/4885PRKAB2 318/4885PRKAG1 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.