Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885758 | 0.78 | MAOA (0.35) | ESR1ESR2MAOAMAOBTAAR1 | |
| SCHEMBL272692 | 0.77 | NR1H2 (0.39) | ESR1ESR2MAOATAAR1SLC6A2 | |
| SCHEMBL14600057 | 0.77 | ESR1 (0.34) | ESR1ESR2MAOATAAR1SLC6A2 | |
| SCHEMBL14600058 | 0.77 | ESR1 (0.34) | ESR1ESR2MAOATAAR1SLC6A2 | |
| SCHEMBL1314169 | 0.77 | ESR1 (0.34) | ESR1ESR2MAOATAAR1SLC6A2 | |
| SCHEMBL12814670 | 0.76 | — | — | |
| SCHEMBL5030059 | 0.74 | AOC3 (0.33) | ESR1ESR2MAOATAAR1SLC6A2 | |
| SCHEMBL1315704 | 0.74 | AOC3 (0.33) | ESR1ESR2MAOATAAR1SLC6A2 | |
| SCHEMBL273159 | 0.74 | ESR1 (0.35) | ESR1ESR2MAOATAAR1SLC6A2 | |
| SCHEMBL6114164 | 0.74 | MAPT (0.32) | ESR1ESR2MAOATAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873316-B2 | Compositions and methods for phosphoramidite and oligonucleotide synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873316-B2 | Compositions and methods for phosphoramidite and oligonucleotide synthesis | RNGTT, POLI, FBL | ESR1 1762/4885ESR2 4090/4885MAOA 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.