Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733035 | 0.86 | KMT2A (0.54) | KMT2AMEN1DPP7TSHRSMN1; SMN2 | |
| SCHEMBL29860851 | 0.81 | F2 (0.49) | KMT2AMEN1DPP7TSHRSMN1; SMN2 | |
| SCHEMBL27415157 | 0.80 | ALDH1A1 (0.54) | KMT2AMEN1DPP7TSHRMAPK1 | |
| SCHEMBL28611807 | 0.80 | ALDH1A1 (0.54) | KMT2AMEN1DPP7TSHRMAPK1 | |
| SCHEMBL31114359 | 0.80 | TSHR (0.67) | KMT2AMEN1TSHRSMN1; SMN2GAA | |
| SCHEMBL3919386 | 0.80 | TSHR (0.71) | KMT2AMEN1TSHRSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL11688129 | 0.77 | TSHR (0.67) | KMT2AMEN1TSHRSMN1; SMN2GAA | |
| SCHEMBL29114695 | 0.77 | TSHR (0.66) | KMT2AMEN1TSHRSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL31580079 | 0.76 | TSHR (0.64) | KMT2AMEN1TSHRSMN1; SMN2GAA | |
| SCHEMBL4732973 | 0.75 | EPHX2 (0.61) | KMT2AMEN1TSHRSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4304586-A1 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | Jnana Therapeutics Inc. (US) | 2024-01-17 | — | — | EP | disclosed |