Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1198337 | 0.87 | KDM4C (0.46) | KMT2AMEN1TSHRALDH1A1TDP1 | |
| SCHEMBL27003454 | 0.86 | KMT2A (0.57) | KMT2AMEN1TSHRALDH1A1KDM4E | |
| SCHEMBL4732973 | 0.85 | EPHX2 (0.61) | KMT2AMEN1TSHRALDH1A1TDP1 | |
| SCHEMBL1198634 | 0.84 | KDM4C (0.49) | KMT2AMEN1TSHRALDH1A1TDP1 | |
| SCHEMBL4733093 | 0.84 | TSHR (0.57) | KMT2AMEN1TSHRALDH1A1TDP1 | |
| SCHEMBL29114695 | 0.83 | TSHR (0.66) | KMT2AMEN1TSHRALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL31580079 | 0.82 | TSHR (0.64) | KMT2AMEN1TSHRALDH1A1TDP1 | |
| SCHEMBL27415157 | 0.82 | ALDH1A1 (0.54) | KMT2AMEN1TSHRALDH1A1TDP1 | |
| SCHEMBL28611807 | 0.82 | ALDH1A1 (0.54) | KMT2AMEN1TSHRALDH1A1TDP1 | |
| SCHEMBL3919386 | 0.81 | TSHR (0.71) | KMT2AMEN1TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |