Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112120 | 0.87 | SLC6A2 (0.34) | TSHR | |
| SCHEMBL18745640 | 0.83 | TSHR (0.58) | TSHRKDM4EL3MBTL1NISCHPKM | |
| SCHEMBL21154977 | 0.82 | GABRA1 (0.40) | TSHR | |
| SCHEMBL17537183 | 0.81 | TSHR (0.50) | TSHRKDM4EL3MBTL1RORC | |
| SCHEMBL17537215 | 0.81 | TSHR (0.50) | TSHRKDM4EL3MBTL1RORC | |
| SCHEMBL17537092 | 0.81 | TSHR (0.50) | TSHRKDM4EL3MBTL1RORC | |
| SCHEMBL17537126 | 0.81 | TSHR (0.50) | TSHRKDM4EL3MBTL1RORC | |
| SCHEMBL17537156 | 0.81 | TSHR (0.50) | TSHRKDM4EL3MBTL1RORC | |
| SCHEMBL17537193 | 0.81 | TSHR (0.50) | TSHRKDM4EL3MBTL1RORC | |
| SCHEMBL17537196 | 0.81 | TSHR (0.50) | TSHRKDM4EL3MBTL1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189834-B1 | USE OF GABAA RECEPTOR REINFORCING AGENT IN PREPARATION OF SEDATIVE AND ANESTHETIC MEDICAMENT | HAISCO INNOVATIVE PHARMACEUTICAL PTE LTD (SG) | 2024-01-17 | — | — | EP | disclosed |