⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1524412 | 0.82 | — | — | |
| SCHEMBL10714720 | 0.66 | — | — | |
| SCHEMBL461723 | 0.62 | — | — | |
| SCHEMBL9562886 | 0.59 | — | — | |
| SCHEMBL7532414 | 0.59 | — | — | |
| SCHEMBL14112763 | 0.57 | ALDH1A1 (0.48) | — | |
| SCHEMBL7272142 | 0.56 | — | — | |
| Hydrogen Peroxide SCHEMBL4633835 | 0.56 | — | — | |
| Guanidine SCHEMBL981791 | 0.55 | — | — | |
| SCHEMBL4870821 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458464-B1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHOROTHIOATE OLIGORIBONUCLEOTIDES | ETH ZUERICH (CH) | 2026-04-15 | — | — | EP | disclosed |
| US-20250236637-A1 | GUANINE-RICH OLIGONUCLEOTIDES | KUROS US LLC | 2025-07-24 | — | — | US | disclosed |
| US-20230416296-A1 | GUANINE-RICH OLIGONUCLEOTIDES | KUROS US LLC | 2023-12-28 | — | — | US | disclosed |
| US-10882884-B2 | Stereoselective synthesis of phosphorothioate oligoribonucleotides | ETH ZURICH (CH) | 2021-01-05 | — | — | US | disclosed |
| US-10435690-B2 | Treatment of alpha-L-iduronidase (IDUA) related diseases by inhibition of natural antisense transcript to IDUA | CURNA, INC. (US) | 2019-10-08 | — | — | US | disclosed |
| EP-3299464-B1 | TREATMENT OF ATONAL HOMOLOG 1 (ATOH1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO ATOH1 | CURNA INC (US) | 2019-10-02 | — | — | EP | disclosed |
| EP-3517613-A1 | TREATMENT OF FIBROBLAST GROWTH FACTOR 21 (FGF21) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO FGF21 | CuRNA, Inc. (US) | 2019-07-31 | — | — | EP | disclosed |
| US-10337011-B2 | Treatment of fibroblast growth factor 21 (FGF21) related diseases by inhibition of natural antisense transcript to FGF21 | CURNA, INC. (US) | 2019-07-02 | — | — | US | disclosed |
| EP-2974740-B1 | HEPATITIS B VACCINE | JIANGSU THERAVAC BIO PHARMACEUTICAL CO LTD (CN) | 2019-06-19 | — | — | EP | disclosed |
| US-20190135849-A1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHOROTHIOATE OLIGORIBONUCLEOTIDES | ETH ZURICH (CH) | 2019-05-09 | — | — | US | disclosed |
| US-20080287670-A1 | Systems and methods for the purification of synthetic trityl-on oligonucleotides | SCOTT GREGORY | 2008-11-20 | — | — | US | disclosed |
| WO-2008073960-A2 | OLIGONUCLEOTIDES CONTAINING HIGH CONCENTRATIONS OF GUANINE MONOMERS | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2008-06-19 | — | — | WO | disclosed |
| US-20080139797-A1 | OLIGONUCLEOTIDES CONTAINING HIGH CONCENTRATIONS OF GUANINE MONOMERS | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2008-06-12 | — | — | US | disclosed |
| EP-1883647-A1 | OLIGONUCLEOTIDES OR THEIR FUNCTIONAL HOMOLOGUES, A COMPOSITION COMPRISING THE SAME AND A METHOD OF TREATING B CELL NEOPLASM | Changchun Huapu Biotechnology Co., Ltd. (CN) | 2008-02-06 | — | — | EP | disclosed |
| EP-1883411-A1 | AN OLIGONUCLEOTIDE OR ITS FUNCTIONAL HOMOLOGUE, A COMPOSITION COMPRISING THE SAME AND A METHOD FOR TREATING B CELL NEOPLASM | Changchun Huapu Biotechnology Co., Ltd. (CN) | 2008-02-06 | — | — | EP | disclosed |
| US-20070155683-A1 | Artificial cpg single-stranded oligodeoxynucleotide and antiviral use thereof | NANJING HUAPU (PARR) BIO PHARMACEUTICALS CO., LTD. (CN) | 2007-07-05 | — | — | US | disclosed |
| US-20070049745-A1 | Oligonucleotide synthesis using periodate salts | THIRD WAVE TECHNOLOGIES, INC. (US) | 2007-03-01 | — | — | US | disclosed |
| WO-2006122464-A1 | AN OLIGONUCLEOTIDE OR ITS FUNCTIONAL HOMOLOGUE, A COMPOSITION COMPRISING THE SAME AND A METHOD FOR TREATING B CELL NEOPLASM | CHANGCHUN HUAPU BIOTECHNOLOGY CO., LTD. (CN) | 2006-11-23 | — | — | WO | disclosed |
| WO-2006122463-A1 | OLIGONUCLEOTIDES OR THEIR FUNCTIONAL HOMOLOGUES, A COMPOSITION COMPRISING THE SAME AND A METHOD OF TREATING B CELL NEOPLASM | CHANGCHUN HUAPU BIOTECHNOLOGY CO., LTD. (CN) | 2006-11-23 | — | — | WO | disclosed |
| EP-1650218-A1 | THE ARTIFICIAL CPG SINGLE STRAND DEOXIDATION OLIGONUCLEOTIDE AND ITS ANTIVIRAL USES | Changchun Huapu Biotechnology Co., Ltd. (CN) | 2006-04-26 | — | — | EP | disclosed |