Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 11/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27005480 | 0.87 | PRKCZ (0.51) | XDHKDM1AMAPK14OPRD1 | |
| SCHEMBL27005539 | 0.85 | KDM1A (0.51) | KDM1A | |
| SCHEMBL27005514 | 0.84 | KDM1A (0.50) | KDM1A | |
| SCHEMBL27005472 | 0.84 | KDM1A (0.50) | KDM1A | |
| SCHEMBL27005051 | 0.83 | KDM1A (0.49) | KDM1A | |
| SCHEMBL27005287 | 0.83 | KDM1A (0.49) | KDM1A | |
| SCHEMBL27005607 | 0.83 | KDM1A (0.47) | XDHKDM1APGRAR | |
| SCHEMBL27004945 | 0.83 | KDM1A (0.56) | KDM1AMAPK14 | |
| SCHEMBL27005639 | 0.81 | KDM1A (0.46) | XDHKDM1A | |
| SCHEMBL27005505 | 0.81 | KDM1A (0.44) | XDHKDM1APGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |