Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27005639 | 0.84 | KDM1A (0.46) | KDM1AXDHCYP11B1CYP11B2SCN9A | |
| SCHEMBL27005505 | 0.84 | KDM1A (0.44) | KDM1AXDHCYP11B1CYP11B2PGR | |
| SCHEMBL27005911 | 0.83 | XDH (0.38) | KDM1AXDHCYP11B1CYP11B2PGR | |
| SCHEMBL27005481 | 0.83 | XDH (0.49) | KDM1AXDHPGRAR | |
| SCHEMBL27005050 | 0.82 | ESR1 (0.48) | CYP11B1CYP11B2AR | |
| SCHEMBL27005480 | 0.81 | PRKCZ (0.51) | KDM1AXDH | |
| SCHEMBL27005774 | 0.78 | KDM1A (0.48) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL27004984 | 0.77 | KDM1A (0.55) | KDM1A | |
| SCHEMBL27005844 | 0.77 | CYP11B1 (0.45) | CYP11B1CYP11B2 | |
| SCHEMBL27009752 | 0.75 | CYP11B1 (0.45) | KDM1ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |