Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.44 |
| ▸ | CFTR | P13569 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27005513 | 0.96 | CFTR (0.46) | KDM1ACFTRGPR119KDM4DSUV39H2 | |
| SCHEMBL27005540 | 0.96 | CFTR (0.46) | KDM1ACFTRGPR119KDM4DSUV39H2 | |
| SCHEMBL27005538 | 0.92 | KDM1A (0.44) | KDM1ACFTRKDM4DSUV39H2 | |
| SCHEMBL27005479 | 0.91 | KDM1A (0.46) | KDM1ACFTRKDM4DSUV39H2 | |
| SCHEMBL27005518 | 0.91 | KDM1A (0.47) | KDM1ACFTRKDM4DSUV39H2 | |
| SCHEMBL31492475 | 0.89 | CFTR (0.43) | KDM1ACFTRGPR119KDM4DSUV39H2 | |
| SCHEMBL27005612 | 0.89 | KDM1A (0.45) | KDM1AGPR119 | |
| SCHEMBL27005506 | 0.87 | GPR119 (0.48) | KDM1ACFTRGPR119 | |
| SCHEMBL26695615 | 0.86 | GPR119 (0.46) | KDM1ACFTRGPR119KDM4D | |
| SCHEMBL27005025 | 0.86 | KDM1A (0.50) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |