⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3063621 | 0.97 | — | — | |
| SCHEMBL100765 | 0.67 | HPGDS (0.46) | — | |
| SCHEMBL13180308 | 0.66 | FAAH (0.37) | — | |
| SCHEMBL28892029 | 0.63 | FAAH (0.39) | — | |
| SCHEMBL1231949 | 0.63 | FAAH (0.47) | — | |
| SCHEMBL11130354 | 0.63 | FAAH (0.39) | — | |
| SCHEMBL25391442 | 0.62 | CCR1 (0.32) | — | |
| SCHEMBL317377 | 0.62 | — | — | |
| SCHEMBL323900 | 0.62 | — | — | |
| SCHEMBL27101 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388531-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARM INNC (US) | 2025-12-25 | — | — | US | disclosed |
| US-20210395189-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. | 2021-12-23 | — | — | US | disclosed |
| EP-3812372-A2 | 7-HETEROCYCLYL SUBSTITUTED SANCYCLINE DERIVATIVES FOR TREATING BACTERIAL, VIRAL AND PARASITIC INFECTIONS (E.G. MALARIA) OR INFLAMMATORY DISEASES | Paratek Pharmaceuticals, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |
| EP-3045449-A1 | TETRACYCLINE DERIVATIVES FOR THE TREATMENT OF BACTERIAL, VIRAL AND PARASITIC INFECTIONS | Paratek Pharmaceuticals, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| US-20160046561-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. | 2016-02-18 | — | — | US | disclosed |
| US-9012433-B2 | Substituted tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2015-04-21 | — | — | US | disclosed |
| US-20130102779-A1 | Substituted Tetracycline Compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2013-04-25 | — | — | US | disclosed |
| US-8318706-B2 | Substituted tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2012-11-27 | — | — | US | disclosed |
| EP-2455367-A1 | Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections | Paratek Pharmaceuticals, Inc. (US) | 2012-05-23 | — | — | EP | disclosed |
| EP-2452935-A2 | Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections | Paratek Pharmaceuticals, Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| EP-2450347-A1 | Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections | Paratek Pharmaceuticals, Inc. (US) | 2012-05-09 | — | — | EP | disclosed |
| US-20100305072-A1 | Substituted Tetracycline Compounds | PARATEK PHARMACEUTICALS, INC. | 2010-12-02 | — | — | US | disclosed |
| EP-2109602-A2 | TETRACYCLINE DERIVATIVES FOR THE TREATMENT OF BACTERIAL, VIRAL AND PARASITIC INFECTIONS | Paratek Pharmaceuticals, Inc. (US) | 2009-10-21 | — | — | EP | disclosed |
| WO-2008106202-A1 | THERAMUTEIN MODULATORS | HOUSEY GERARD M (US) | 2008-09-04 | — | — | WO | disclosed |
| WO-2008079339-A2 | TETRACYCLINE DERIVATIVES FOR THE TREATMENT OF BACTERIAL, VIRAL AND PARASITIC INFECTIONS | PARATEK PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |