⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604 | 0.85 | TSHR (0.48) | — | |
| Bromide SCHEMBL11831501 | 0.83 | TSHR (0.46) | — | |
| SCHEMBL8326 | 0.83 | TSHR (0.52) | — | |
| SCHEMBL2003226 | 0.81 | TSHR (0.50) | — | |
| SCHEMBL2313991 | 0.75 | NOS3 (0.48) | — | |
| SCHEMBL11531367 | 0.74 | NOS3 (0.33) | — | |
| SCHEMBL688175 | 0.72 | NOS3 (0.56) | — | |
| SCHEMBL3523540 | 0.72 | — | — | |
| SCHEMBL1436400 | 0.72 | PARP10 (0.40) | — | |
| SCHEMBL446945 | 0.70 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 9079 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752497-B1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | claimed |
| CN-118121600-A | Small molecule modulation of spike proteins | 北京生命科学研究所 | 2024-06-04 | — | — | CN | claimed |
| CN-118047801-A | KRAS inhibitor compound, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| EP-4361141-A1 | PROTEIN DEGRADATION AGENT | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2024-05-01 | — | — | EP | claimed |
| CN-117903016-A | Fluorosulfonyl sulfonimide salt, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2024-04-19 | — | — | CN | claimed |
| WO-2024074641-A1 | METHOD FOR PREPARING AMIDES FROM ESTERS | BASF SE (DE) | 2024-04-11 | — | — | WO | claimed |
| US-20240116910-A1 | Heterocycles as WIP1 Inhibitors | PMV PHARMACEUTICALS, INC. | 2024-04-11 | — | — | US | claimed |
| CN-117794899-A | Novel heterocyclic compounds, compositions, methods of preparation and uses thereof | 欧加农研发芬兰有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117545749-A | Protein degradation agent | 苏州开拓药业股份有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-113423709-B | Triazinone imidazole compound and medical application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-09 | — | — | CN | claimed |
| US-4468511-A | C-20- And C-23-Modified macrolide derivatives | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | claimed |
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | claimed |
| EP-0106800-A1 | Furans | CIBA-GEIGY AG (CH) | 1984-04-25 | — | — | EP | claimed |
| EP-0103465-A1 | 20-Amino macrolide derivatives | ELI LILLY AND COMPANY (US) | 1984-03-21 | — | — | EP | claimed |
| EP-0101023-A1 | Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-02-22 | — | — | EP | claimed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | claimed |
| EP-0078241-A2 | Furanes | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | claimed |
| EP-0051278-A1 | Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-05-12 | — | — | EP | claimed |
| EP-0039051-A2 | Mannich-base hydroxamic acid prodrugs for the improved bioavailability of non-steroidal anti-inflammatory agents, a process for preparing and a pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1981-11-04 | — | — | EP | claimed |
| US-3975379-A | METHINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | claimed |