Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11831501 | 0.98 | TSHR (0.46) | TSHRNOS3NOS2NOS1NPC1 | |
| SCHEMBL8326 | 0.93 | TSHR (0.52) | TSHRNOS3NOS2NOS1NPC1 | |
| SCHEMBL2003226 | 0.91 | TSHR (0.50) | TSHRNOS3NOS2NOS1NPC1 | |
| SCHEMBL27008 | 0.85 | — | — | |
| SCHEMBL14999656 | 0.75 | TSHR (0.52) | TSHRNOS3NOS2NOS1NPC1 | |
| SCHEMBL7344549 | 0.73 | CD44 (0.45) | MAPTMAOBMEN1CYP3A4KMT2A | |
| SCHEMBL2313991 | 0.71 | NOS3 (0.48) | TSHRNOS3NOS2NOS1NPC1 | |
| SCHEMBL224421 | 0.71 | SIGMAR1 (0.54) | ALDH1A1 | |
| SCHEMBL221597 | 0.71 | SIGMAR1 (0.54) | NOS3NOS2NOS1ALDH1A1 | |
| SCHEMBL11531367 | 0.70 | NOS3 (0.33) | NOS3NOS2NOS1MAPTTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 15527 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752497-B1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | claimed |
| CN-118324743-A | Nav1.8 inhibitor and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-12 | — | — | CN | claimed |
| CN-118317951-A | Phthalazine derivatives as pyruvate kinase modulators | 西特瑞治疗有限公司 | 2024-07-09 | — | — | CN | claimed |
| EP-4389130-A1 | APPLICATION OF STEROID COMPOUND IN PREPARATION OF DRUG FOR PREVENTING AND/OR TREATING EYE FLOATERS | Guangzhou Ocusun Ophthalmic Biotechnology Co., Ltd. (CN) | 2024-06-26 | — | — | EP | claimed |
| US-20240199638-A1 | GLUTARIMIDES FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | US | claimed |
| EP-4385985-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-06-19 | — | — | EP | claimed |
| CN-118201929-A | PROTAC compound, pharmaceutical composition containing same, and preparation method and application thereof | 广东弘烨医药科技有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118176004-A | Use of steroid compounds for the prevention and/or treatment of cataracts | 广州润尔眼科生物科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-118139864-A | New compounds | 西特瑞治疗有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-118108706-A | Glutarimide | C4医药公司 | 2024-05-31 | — | — | CN | claimed |
| EP-0008746-A1 | Alpha-(N-arylsulfonyl-L-argininamides, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1980-03-19 | — | — | EP | claimed |
| EP-0005380-A2 | Phototropic photosensitive compositions containing a fluoran colorformer | Dynachem Corporation (US) | 1979-11-14 | — | — | EP | claimed |
| EP-0005379-A2 | Photosensitive compositions containing carbonylic halides as activators | Dynachem Corporation (US) | 1979-11-14 | — | — | EP | claimed |
| US-4140681-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1979-02-20 | — | — | US | claimed |
| US-4131673-A | INHIBITION AND SUPPRESSION OF THROMBOSIS IN MAMMALS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1978-12-26 | — | — | US | claimed |
| US-4125604-A | PEPTIDES, ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-11-14 | — | — | US | claimed |
| US-4117127-A | INHIBITION AND SUPPRESSION OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1978-09-26 | — | — | US | claimed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | claimed |
| US-4101653-A | ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-07-18 | — | — | US | claimed |
| US-4093712-A | ANTITHROMBOGENIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-06-06 | — | — | US | claimed |