Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27008600 | 0.85 | KMT2A (0.42) | MAP4K1NAMPTCDK5CDK5R1 | |
| SCHEMBL27008427 | 0.85 | KMT2A (0.42) | MAP4K1NAMPTCDK5CDK5R1 | |
| SCHEMBL27008525 | 0.84 | MAP4K1 (0.37) | KCNH2MAP4K1NAMPTLRRK2LMNA | |
| SCHEMBL27008631 | 0.84 | ALDH1A1 (0.42) | MAP4K1NAMPTALDH1A1 | |
| SCHEMBL27008430 | 0.84 | ALDH1A1 (0.42) | MAP4K1NAMPTALDH1A1 | |
| SCHEMBL27008529 | 0.84 | ALDH1A1 (0.38) | KCNH2MAP4K1NAMPTLRRK2LMNA | |
| SCHEMBL27008610 | 0.84 | ALDH1A1 (0.38) | KCNH2MAP4K1NAMPTLRRK2LMNA | |
| SCHEMBL24433494 | 0.80 | MGLL (0.47) | — | |
| SCHEMBL29656730 | 0.80 | MGLL (0.47) | — | |
| SCHEMBL29911426 | 0.80 | MGLL (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018120-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018120-A1 | MAGL INHIBITORS | MAG, MAGI3, MAGT1 | KCNH2 2917/4885MAP4K1 510/4885NAMPT 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.