Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 15/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12906161 | 0.71 | NOTUM (0.59) | NOTUMMAPTTLR8ALDH1A1HPGD | |
| SCHEMBL87533 | 0.71 | — | — | |
| SCHEMBL11116512 | 0.69 | NOTUM (0.39) | NOTUMMAPTTLR8ALDH1A1TSHR | |
| SCHEMBL30645081 | 0.65 | NOTUM (0.48) | NOTUMMAPTTLR8ALDH1A1HPGD | |
| SCHEMBL20523585 | 0.64 | — | — | |
| SCHEMBL6411696 | 0.64 | — | — | |
| SCHEMBL440423 | 0.64 | NOTUM (0.42) | NOTUMMAPTTLR8ALDH1A1TSHR | |
| SCHEMBL12446805 | 0.64 | NOTUM (0.66) | NOTUMTLR8 | |
| SCHEMBL24921991 | 0.63 | ALDH1A1 (0.47) | NOTUMMAPTTLR8ALDH1A1HPGD | |
| SCHEMBL21963964 | 0.63 | NOTUM (0.58) | NOTUMTLR8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024013690-A1 | 1,3,4-OXADIAZOLE TRIAZOLE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-01-18 | — | — | WO | claimed |
| WO-2024013690-A1 | 1,3,4-OXADIAZOLE TRIAZOLE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-01-18 | — | — | WO | disclosed |
| WO-2024013690-A1 | 1,3,4-OXADIAZOLE TRIAZOLE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-01-18 | — | — | WO | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |