SCHEMBL27009299

SCHEMBL27009299

CCOC(=O)C(N)CCCCNC

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.42
NOD1 Q9Y239 4/20 0.42
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
CPB2 Q96IY4 2/20 0.39
RRM1 P23921 1/20 0.36
TP53 P04637 1/20 0.35
KISS1R Q969F8 1/20 0.35
SLC15A1 P46059 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15148457 0.85 DPP7 (0.41) DPP7GNAI3GNAO1GNAI1CPB2
SCHEMBL18235900 0.84 NOD1 (0.41) DPP7NOD1GNAI3GNAO1GNAI1
SCHEMBL23280941 0.83 NOD1 (0.40) DPP7NOD1GNAI3GNAO1GNAI1
SCHEMBL27900093 0.83 KDM4E (0.48) DPP7NOD1GNAI3GNAO1GNAI1
SCHEMBL594596 0.83 KDM4E (0.48) DPP7NOD1GNAI3GNAO1GNAI1
SCHEMBL12643957 0.83 KDM4E (0.48) DPP7NOD1GNAI3GNAO1GNAI1
SCHEMBL19223347 0.81 TDP1 (0.46) CPB2KISS1RPOLBKMT2A
Hydrochloric Acid SCHEMBL28854821 0.81 KDM4E (0.47) DPP7NOD1GNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL28854822 0.81 KDM4E (0.47) DPP7NOD1GNAI3GNAO1GNAI1
SCHEMBL11296849 0.81 NOD1 (0.52) DPP7NOD1GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025866-A1 SYNTHESIS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS NOVARTIS AG (CH) 2024-01-25 US disclosed
US-20240018099-A1 SYNTHESIS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS NOVARTIS AG (CH) 2024-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025866-A1 SYNTHESIS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS FOLH1, KLK3, BPHL DPP7 715/4885NOD1 4531/4885GNAI3 787/4885
US-20240018099-A1 SYNTHESIS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS FOLH1, KLK3, BPHL DPP7 715/4885NOD1 4531/4885GNAI3 787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.