Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.45 |
| ▸ | KDM1A | O60341 | 13/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27009856 | 0.91 | CYP11B1 (0.43) | CYP11B1CYP11B2KDM1A | |
| SCHEMBL27010074 | 0.85 | KDM1A (0.37) | CYP11B1CYP11B2KDM1AEGLN2PTGS2 | |
| SCHEMBL27009402 | 0.84 | AR (0.48) | KDM1A | |
| SCHEMBL27009932 | 0.78 | AR (0.48) | KDM1A | |
| SCHEMBL27005050 | 0.77 | ESR1 (0.48) | CYP11B1CYP11B2 | |
| SCHEMBL27005607 | 0.75 | KDM1A (0.47) | CYP11B1CYP11B2KDM1A | |
| SCHEMBL27008961 | 0.75 | KDM1A (0.42) | KDM1A | |
| SCHEMBL27005774 | 0.75 | KDM1A (0.48) | CYP11B1CYP11B2KDM1APTGS2 | |
| SCHEMBL27005844 | 0.74 | CYP11B1 (0.45) | CYP11B1CYP11B2EGLN2 | |
| SCHEMBL30895187 | 0.74 | CYP11B1 (0.51) | CYP11B1CYP11B2KDM1AEGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |