Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27005770 | 0.84 | KDM1A (0.49) | KDM1AMAPTHSD17B10ALOX15HTT | |
| SCHEMBL27005050 | 0.80 | ESR1 (0.48) | MAPTCYP11B1CYP11B2EPAS1 | |
| SCHEMBL27005607 | 0.78 | KDM1A (0.47) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL27006151 | 0.76 | EGLN2 (0.39) | CYP11B1CYP11B2 | |
| SCHEMBL27009752 | 0.75 | CYP11B1 (0.45) | KDM1APTGS2CYP11B1CYP11B2 | |
| SCHEMBL27005844 | 0.74 | CYP11B1 (0.45) | CYP11B1CYP11B2 | |
| SCHEMBL27005847 | 0.74 | KDM1A (0.50) | KDM1ACYP11B1CYP11B2EPAS1GSK3B | |
| SCHEMBL27005741 | 0.72 | KDM1A (0.47) | KDM1ACYP11B1CYP11B2EPAS1 | |
| SCHEMBL27010074 | 0.72 | KDM1A (0.37) | KDM1APTGS2CYP11B1CYP11B2EPAS1 | |
| SCHEMBL27006058 | 0.72 | CYP11B2 (0.45) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |