SCHEMBL2700980

SCHEMBL2700980

CC(C)(C)OC(=O)Nc1ccc(-c2noc(C(F)(F)F)n2)cc1

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 19/20 0.61
HDAC6 Q9UBN7 11/20 0.61
HDAC8 Q9BY41 2/20 0.53
HDAC1 Q13547 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10553693 0.89 HDAC4 (0.64) HDAC4HDAC6HDAC8HDAC1
SCHEMBL10556701 0.84 HDAC4 (0.62) HDAC4HDAC6HDAC8HDAC1
SCHEMBL10557808 0.84 HDAC4 (0.63) HDAC4HDAC6
SCHEMBL21888814 0.83 HDAC4 (0.47) HDAC4HDAC6HDAC8HDAC1
SCHEMBL10552633 0.83 HDAC4 (0.67) HDAC4HDAC6HDAC8HDAC1
SCHEMBL14934180 0.82 HDAC4 (0.62) HDAC4HDAC6HDAC8HDAC1
SCHEMBL29395730 0.82 HDAC4 (0.66) HDAC4HDAC6HDAC8
SCHEMBL20642848 0.82 SCD (0.55) HDAC4HDAC6HDAC8HDAC1
SCHEMBL24168679 0.82 HDAC4 (0.48) HDAC4HDAC6HDAC8HDAC1
SCHEMBL30334742 0.82 HDAC4 (0.48) HDAC4HDAC6HDAC8HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486240-B2 Oxadiazole compounds for controlling or preventing phytopathogenic fungi PI INDUSTRIES LTD. (IN) 2025-12-02 US disclosed
US-20240358020-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-10-31 US disclosed
CN-117693500-A Carboxamide derivative and agricultural/horticultural plant disease control agent 组合化学工业株式会社 2024-03-12 CN disclosed
EP-3953340-B1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD (IN) 2023-08-02 EP disclosed
WO-2023286855-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT クミアイ化学工業株式会社 2023-01-19 WO disclosed
US-20220135531-A1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2022-05-05 US disclosed
EP-3953340-A1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI PI Industries Ltd. (IN) 2022-02-16 EP disclosed
CN-114026077-A Novel oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2022-02-08 CN disclosed
US-20210002232-A1 HETEROCYCLIC COMPOUNDS AS FUNGICIDES PI INDUSTRIES LTD. (IN) 2021-01-07 US disclosed
WO-2019171234-A9 HETEROCYCLIC COMPOUNDS AS FUNGICIDES PI INDUSTRIES LTD. (IN) 2020-01-09 WO disclosed
WO-2019171234-A1 HETEROCYCLIC COMPOUNDS AS FUNGICIDES PI INDUSTRIES LTD. (IN) 2019-09-12 WO disclosed
EP-2194046-B1 Triazolone derivative EISAI R&D MAN CO LTD (JP) 2012-05-09 EP disclosed
US-7816522-B2 Triazolone derivatives EISAI CO., LTD. (JP) 2010-10-19 US disclosed
EP-2194046-A1 Triazolone derivative Eisai R&D Management Co., Ltd. (JP) 2010-06-09 EP disclosed
EP-2000465-A1 TRIAZOLONE DERIVATIVE Eisai R&D Management Co., Ltd. (JP) 2008-12-10 EP disclosed
US-20080015199-A1 Triazolone derivatives EISAI R&D MANAGEMENT CO., LTD. (JP) 2008-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002232-A1 HETEROCYCLIC COMPOUNDS AS FUNGICIDES CYP1A2, CYP1B1, CYP1A1 HDAC4 948/4885HDAC6 731/4885HDAC8 859/4885
US-12486240-B2 Oxadiazole compounds for controlling or preventing phytopathogenic fungi OXA1L, CYP51A1, ERG28 HDAC4 2763/4885HDAC6 1436/4885HDAC8 2680/4885
US-20240358020-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT INF2, BROX, AFF2 HDAC4 352/4885HDAC6 259/4885HDAC8 771/4885
US-20220135531-A1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI OXA1L, FBXL19, ERG28 HDAC4 2616/4885HDAC6 1269/4885HDAC8 2467/4885
US-20080015199-A1 Triazolone derivatives F3, F12, F2 HDAC4 637/4885HDAC6 236/4885HDAC8 803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.