Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27010262 | 0.89 | CYP2D6 (0.40) | EPHX2CYP3A4PIK3CDCYP2C19ALDH1A1 | |
| SCHEMBL7919663 | 0.88 | EPHX2 (0.45) | EPHX2CYP3A4PIK3CDCYP2C19ALDH1A1 | |
| SCHEMBL23077805 | 0.84 | SMN1; SMN2 (0.43) | EPHX2CYP3A4PIK3CDCYP1A2TDP1 | |
| SCHEMBL25900589 | 0.80 | CYP2C9 (0.49) | CYP3A4CYP2C19ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL8029490 | 0.79 | DPP4 (0.45) | EPHX2CYP3A4PIK3CDCYP2C19ALDH1A1 | |
| SCHEMBL12259478 | 0.76 | PIK3CD (0.38) | EPHX2CYP3A4PIK3CDCYP2C19ALDH1A1 | |
| SCHEMBL3434463 | 0.74 | EPHX2 (0.55) | EPHX2CYP3A4PIK3CDCYP2C19ALDH1A1 | |
| SCHEMBL12921202 | 0.74 | SMN1; SMN2 (0.39) | EPHX2CYP3A4PIK3CDCYP2C19ALDH1A1 | |
| SCHEMBL24317731 | 0.74 | SMN1; SMN2 (0.39) | EPHX2CYP3A4PIK3CDCYP2C19ALDH1A1 | |
| SCHEMBL17172988 | 0.74 | SMN1; SMN2 (0.39) | EPHX2CYP3A4PIK3CDCYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C 4 Therapeutics, Inc. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | NFATC1, CTSS, MMP12 | EPHX2 2867/4885CYP3A4 2566/4885PIK3CD 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.