Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPOR | P19235 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27012310 | 0.89 | FOLH1 (0.47) | FOLH1ALDH1A1HTTEPORCPA3 | |
| SCHEMBL20510546 | 0.87 | FOLH1 (0.47) | FOLH1ALDH1A1HTTEPORCPA3 | |
| SCHEMBL20510550 | 0.87 | FOLH1 (0.47) | FOLH1ALDH1A1HTTEPORCPA3 | |
| SCHEMBL25772689 | 0.85 | FOLH1 (0.54) | FOLH1ALDH1A1HTTEPORCPA3 | |
| SCHEMBL18901917 | 0.85 | ALDH1A1 (0.51) | ALDH1A1HCAR2MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL824998 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HCAR2MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL634623 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HCAR2MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL27009223 | 0.82 | ALDH1A1 (0.47) | FOLH1ALDH1A1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL27012372 | 0.81 | FOLH1 (0.48) | FOLH1ALDH1A1HTTKMT2AMAPT | |
| SCHEMBL3791586 | 0.80 | EPOR (0.47) | FOLH1ALDH1A1HTTEPORCPA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016946-A1 | DRUG-LOADED MACROMOLECULE AND PREPARATION METHOD THEREFOR | SHANGHAI SHENGDI PHARMACEUTICAL CO., LTD. (CN) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016946-A1 | DRUG-LOADED MACROMOLECULE AND PREPARATION METHOD THEREFOR | MRPL38, MRPS27, MRPS18A | FOLH1 233/4885ALDH1A1 2240/4885HTT 2706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.