Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824998 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HCAR2L3MBTL1TDP1MAPK1 | |
| Trifluoroacetic Acid SCHEMBL27873675 | 0.92 | ALDH1A1 (0.43) | ALDH1A1HCAR2L3MBTL1TDP1MAPK1 | |
| SCHEMBL18901917 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HCAR2L3MBTL1TDP1MAPK1 | |
| SCHEMBL15448254 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HCAR2L3MBTL1TDP1MAPK1 | |
| SCHEMBL12799366 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HCAR2L3MBTL1TDP1MAPK1 | |
| SCHEMBL10315706 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HCAR2L3MBTL1TDP1MAPK1 | |
| SCHEMBL27012170 | 0.84 | FOLH1 (0.49) | ALDH1A1HCAR2L3MBTL1TDP1MAPK1 | |
| SCHEMBL12619862 | 0.79 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TDP1MAPK1KMT2A | |
| SCHEMBL842166 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HCAR2L3MBTL1TDP1MAPK1 | |
| SCHEMBL20363032 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HCAR2L3MBTL1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |
| EP-2513091-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-04-12 | — | — | EP | disclosed |
| EP-2499132-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-02-15 | — | — | EP | disclosed |
| CN-102448956-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-05-06 | — | — | CN | disclosed |
| CN-102459250-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-05-06 | — | — | CN | disclosed |
| CN-102459281-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-03-11 | — | — | CN | disclosed |
| CN-102378762-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2014-10-29 | — | — | CN | disclosed |
| CN-102712628-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-101998952-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2014-10-08 | — | — | CN | disclosed |
| CN-102712623-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-04-02 | — | — | CN | disclosed |
| CN-102459281-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-05-16 | — | — | CN | disclosed |
| CN-102459239-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-05-16 | — | — | CN | disclosed |
| CN-102459250-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-05-16 | — | — | CN | disclosed |
| CN-102448956-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-05-09 | — | — | CN | disclosed |
| CN-102378762-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-03-14 | — | — | CN | disclosed |
| EP-2419433-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-02-22 | — | — | EP | disclosed |
| CN-102007122-A | Imidazolyl biphenyl imidazoles as hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-04-06 | — | — | CN | disclosed |
| CN-101998952-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-03-30 | — | — | CN | disclosed |
| WO-2010120621-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-21 | — | — | WO | disclosed |
| CN-101754966-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2010-06-23 | — | — | CN | disclosed |