SCHEMBL270134

SCHEMBL270134

CCC(=O)C(C)(C)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.57
KMT2A Q03164 1/20 0.57
OPRM1 P35372 4/20 0.53
DRD3 P35462 2/20 0.53
DRD2 P14416 1/20 0.53
CYP2C19 P33261 1/20 0.50
HIF1A Q16665 1/20 0.50
GRIN2D O15399 2/20 0.49
GRIN1 Q05586 2/20 0.49
GRIN2A Q12879 2/20 0.49
GRIN2B Q13224 2/20 0.49
GRIN2C Q14957 2/20 0.49
OPRD1 P41143 2/20 0.49
CACNA1F O60840 1/20 0.49
ABCB1 P08183 1/20 0.49
CYP2B6 P20813 1/20 0.49
DRD4 P21917 1/20 0.49
OPRK1 P41145 1/20 0.49
CACNA1D Q01668 1/20 0.49
KCNH2 Q12809 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28430563 0.83 MAPT (0.53) MAPTKMT2AOPRM1DRD3DRD2
SCHEMBL28602564 0.83 MAPT (0.57) MAPTKMT2AOPRM1DRD3DRD2
SCHEMBL4447460 0.83 KMT2A (0.57) MAPTKMT2AOPRM1DRD3DRD2
SCHEMBL12883298 0.83 HDAC3 (0.53) MAPTKMT2AOPRM1DRD3DRD2
SCHEMBL5331416 0.81 MAPT (0.55) MAPTKMT2AOPRM1DRD3DRD2
SCHEMBL26790274 0.81 NPC1 (0.47) MAPTKMT2AOPRM1DRD3DRD2
Propionic Acid SCHEMBL27754812 0.81 MAPT (0.55) MAPTKMT2AOPRM1DRD3DRD2
SCHEMBL10293315 0.81 OPRM1 (0.51) MAPTKMT2AOPRM1DRD3DRD2
SCHEMBL6610803 0.81 MAPT (0.55) MAPTKMT2AOPRM1DRD3DRD2
SCHEMBL12282314 0.81 OPRM1 (0.51) MAPTKMT2AOPRM1DRD3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1489109-B1 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation CHEVRON ORONITE CO (US) 2015-08-19 EP claimed
CN-102007149-B Production of vinylidene-terminated polyolefins via quenching with monosulfides CHEVRON ORONITE CO 2013-06-19 CN claimed
US-8394897-B2 Production of vinylidene-terminated polyolefins via quenching with monosulfides CHEVRON ORONITE COMPANY LLC (US) 2013-03-12 US claimed
US-8362153-B2 Have improved low temperature and high temperature viscometric properties; sulfonating polyisobutene and reacting the polyisobutenyl sulfonate with an alkali metal or alkaline earth metal CHEVRON ORONITE COMPANY LLC (US) 2013-01-29 US claimed
US-8063154-B2 Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-11-22 US claimed
US-8013073-B2 Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds CHEVRON ORONITE COMPANY LLC (US) 2011-09-06 US claimed
CN-102007149-A Production of vinylidene-terminated polyolefins via quenching with monosulfides CHEVRON ORONITE CO 2011-04-06 CN claimed
US-7816459-B2 Method for preparing polyolefins containing vinylidine end groups using polymeric nitrogen compounds CHEVRON ORONITE COMPANY LLC (US) 2010-10-19 US claimed
EP-1803751-B1 Method for preparing polyolefins containing vinylidene end groups using polymeric nitrogen compounds CHEVRON ORONITE CO (US) 2010-06-30 EP claimed
EP-1803748-B1 Method for preparing polyolefins containing vinylidene end groups using nonaromatic heterocyclic compounds CHEVRON ORONITE CO (US) 2010-06-09 EP claimed
US-20070155911-A1 Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds UNIVERSITY OF SOUTHERN MISSISSIPPI 2007-07-05 US claimed
US-20070155910-A1 Method for preparing polyolefins containing vinylidine end groups using polymeric nitrogen compounds CHEVRON ORONITE COMPANY LLC 2007-07-05 US claimed
EP-1803751-A1 Method for preparing polyolefins containing vinylidene end groups using polymeric nitrogen compounds Chevron Oronite Company LLC (US) 2007-07-04 EP claimed
EP-1803748-A1 Method for preparing polyolefins containing vinylidene end groups using nonaromatic heterocyclic compounds Chevron Oronite Company LLC (US) 2007-07-04 EP claimed
EP-1803741-A1 Method for preparing polyolefins containing vinylidene groups using azole compounds Chevron Oronite Company LLC (US) 2007-07-04 EP claimed
US-20050282972-A1 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers STOKES CASEY D 2005-12-22 US claimed
US-20040260033-A1 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation UNIVERSITY OF SOUTHERN MISSISSIPPI 2004-12-23 US claimed
EP-1489109-A2 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation Chevron Oronite Company LLC (US) 2004-12-22 EP claimed
EP-0341012-B1 UNIFORM MOLECULAR WEIGHT POLYMERS EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1992-12-30 EP claimed
EP-0341012-A2 Uniform molecular weight polymers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-11-08 EP claimed