SCHEMBL27014754

SCHEMBL27014754

Brc1cccc2ccc3[nH]c4ccc(-c5ccccc5)cc4c3c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 8/20 0.57
CCND1 P24385 8/20 0.57
DYRK3 O43781 1/20 0.39
CLK1 P49759 1/20 0.39
CLK2 P49760 1/20 0.39
CLK3 P49761 1/20 0.39
GSK3B P49841 1/20 0.39
CDK5 Q00535 1/20 0.39
DYRK1A Q13627 1/20 0.39
CDK5R1 Q15078 1/20 0.39
DYRK2 Q92630 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
DYRK1B Q9Y463 1/20 0.39
JAK2 O60674 1/20 0.38
NPC1 O15118 1/20 0.37
WEE1 P30291 2/20 0.37
CHEK1 O14757 1/20 0.37
ATM Q13315 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
CCNB2 O95067 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27014722 0.90 CDK4 (0.58) CDK4CCND1DYRK3CLK1CLK2
SCHEMBL17001234 0.88 CDK4 (0.55) CDK4CCND1DYRK3CLK1CLK2
SCHEMBL27014698 0.83 CDK4 (0.49) CDK4CCND1DYRK3CLK1CLK2
SCHEMBL27014751 0.82 AR (0.43) CDK4CCND1NPC1ATMRXFP1
SCHEMBL29655513 0.82 CDK4 (0.49) CDK4CCND1ATMCCNB2CCNE2
SCHEMBL20071605 0.82 CDK4 (0.49) CDK4CCND1ATMCCNB2CCNE2
SCHEMBL23609819 0.80 CDK4 (0.73) CDK4CCND1DYRK3CLK1CLK2
SCHEMBL17563211 0.80 CDK4 (0.73) CDK4CCND1DYRK3CLK1CLK2
SCHEMBL17001254 0.78 GABRP (0.44) CDK4CCND1WEE1CHEK1ATM
SCHEMBL13828829 0.77 CDK4 (0.59) CDK4CCND1ATMRXFP1CCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023433-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME, MANUFACTURING METHOD OF THE SAME AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2024-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240023433-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME, MANUFACTURING METHOD OF THE SAME AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE CYP1A1, CYP1B1, CYP2C9 CDK4 398/4885CCND1 240/4885DYRK3 4610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.