Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 6/20 | 0.49 |
| ▸ | CCND1 | P24385 | 6/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.49 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | PRKACG | P22612 | 1/20 | 0.49 |
| ▸ | PRKACB | P22694 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.49 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20071605 | 1.00 | CDK4 (0.49) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL20065822 | 0.88 | CDK4 (0.47) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL27097802 | 0.87 | CDK4 (0.56) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL420335 | 0.85 | IMPDH2 (0.59) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL29724222 | 0.85 | IMPDH2 (0.59) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL31259489 | 0.83 | IMPDH2 (0.57) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL27014751 | 0.83 | AR (0.43) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL22013016 | 0.83 | CDK4 (0.59) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL24549288 | 0.82 | CDK4 (0.40) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL28238381 | 0.82 | CDK4 (0.59) | CDK4CCND1CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372261-B | Method for preparing 1-bromo/chloro carbazole and derivatives thereof | 中国科学院兰州化学物理研究所 | 2023-06-27 | — | — | CN | disclosed |
| CN-116120353-A | Carbazole derivative containing boron atom and application thereof | 北京八亿时空液晶科技股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-113620811-B | Halogenation method of aromatic compound | 中国科学院兰州化学物理研究所 | 2022-05-24 | — | — | CN | disclosed |