SCHEMBL27018458

SCHEMBL27018458

Clc1cccc(-c2ccc3c(c2)oc2ccccc23)c1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.49
ALOX5 P09917 1/20 0.43
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
PRKDC P78527 1/20 0.39
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
FABP4 P15090 2/20 0.38
MMP12 P39900 1/20 0.38
MMP13 P45452 1/20 0.38
TTR P02766 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
CYP2A6 P11509 1/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27018508 0.94 AHR (0.49) AHRALOX5MEN1MAPTKMT2A
SCHEMBL27018491 0.93 AHR (0.45) AHRALOX5MEN1MAPTKMT2A
SCHEMBL27018509 0.93 AHR (0.47) AHRALOX5MEN1MAPTKMT2A
SCHEMBL27018464 0.91 AHR (0.49) AHRALOX5MEN1MAPTKMT2A
SCHEMBL31312496 0.88 BACE1 (0.38) AHRMEN1KMT2ACA1CA2
SCHEMBL29671023 0.87 AHR (0.42) AHRALOX5MEN1MAPTKMT2A
SCHEMBL26597160 0.87 AHR (0.42) AHRALOX5MEN1MAPTKMT2A
SCHEMBL27018512 0.86 AHR (0.49) AHRALOX5MEN1MAPTKMT2A
SCHEMBL21037633 0.85 AHR (0.58) AHRALOX5MEN1MAPTKMT2A
SCHEMBL21742518 0.83 ALDH1A1 (0.44) AHRALOX5MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023428-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2024-01-18 US disclosed
US-20240023428-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2024-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240023428-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE L1CAM, EPCAM, SELE AHR 4654/4885ALOX5 1055/4885MEN1 1566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.