Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | EIF2AK3 | Q9NZJ5 | 11/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KIF5B | P33176 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407781 | 0.80 | SRC (0.55) | METAXLEIF2AK3FLT3KDR | |
| SCHEMBL22677981 | 0.80 | SRC (0.55) | METAXLEIF2AK3FLT3KDR | |
| SCHEMBL25129546 | 0.79 | BTK (0.44) | BTKKDRLCKTEKMETTL3 | |
| SCHEMBL29407696 | 0.78 | BTK (0.43) | BTKKDRLCKTEKMETTL3 | |
| SCHEMBL25129489 | 0.78 | BTK (0.43) | BTKKDRLCKTEKMETTL3 | |
| SCHEMBL22418477 | 0.78 | TEK (0.52) | METAXLEIF2AK3FLT3KDR | |
| SCHEMBL23917434 | 0.78 | SRC (0.61) | METAXLFLT3KDRLCK | |
| SCHEMBL31264760 | 0.77 | EIF2AK3 (0.50) | METAXLEIF2AK3 | |
| SCHEMBL31264739 | 0.76 | EIF2AK3 (0.49) | METAXLEIF2AK3 | |
| SCHEMBL22658912 | 0.75 | METTL3 (0.42) | BTKKDRLCKTEKMETTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306529-A2 | FGFR INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |